Evidence map›Paper›PMID 27308253›Full record

ArticleInternational journal of critical illness and injury science

Traumatic brain injury related research in India: An overview of published literature.

Amit Agrawal, Ashok Munivenkatappa, Dhaval P Shukla, Geetha R Menon, Rajesh Alogolu, Sagar Galwankar, Saginela Satish Kumar, Pathapati Rama Momhan, Ranabir Pal, Neeti Rustagi

Registry-linked trialAbstract read
In one paragraph

Article in International journal of critical illness and injury science. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07072624 (Assessing Phenytoin and Levetiracetam Efficacy, Cost-Effectiveness, and CYP2C9/SV2A Polymorphism in Early Post-Traumatic Seizures), which is not on this map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07072624 phase4recruitingnot on this map

Assessing Phenytoin and Levetiracetam Efficacy, Cost-Effectiveness, and CYP2C9/SV2A Polymorphism in Early Post-Traumatic Seizures: A Multicentric Prospective Randomized Trial

TypeinterventionalSponsorAll India Institute of Medical Sciences, JodhpurRan2025 to 2028Enrolled1,260ConditionsSeizures, Traumatic Brain Injuries, Traumatic Brain Injury (TBI) PatientsArmsPhenytoin, Levetiracetam, Placebo
3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Article
  2. Review
  3. Observational
  4. Article
  5. Article
  6. Article
  7. Prehospital Impact on Family Members of Road Traffic Accident.Journal of neurosciences in rural practice · 2021
    Article
  8. Article
  9. Article
  10. Burden and Psychological Distress of Intensive Care Unit Caregivers of Traumatic Brain Injury Patients.Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2019
    Article
  11. Article
  12. Traumatic brain injury registry: Need of the hour.Journal of neurosciences in rural practice
    Article
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Amit AgrawalDepartment of Neurosurgery, Narayana Medical College and Hospitals, Nellore, Andhra Pradesh, India.
Ashok MunivenkatappaDepartment of Clinical Neurosciences, National Institute of Mental Health and Neurosciences, Bangalore, Karnataka, India; Department of VDRL Project, National Institute of Epidemiology, Chennai, Tamil Nadu, India.
Dhaval P ShuklaDepartment of Neurosurgery, National Institute of Mental Health and Neurosciences, Bangalore, Karnataka, India.
Geetha R MenonDepartment of Health Research (Ministry of Health and Family Welfare), Division of Non-Communicable Diseases, Indian Council of Medical Research, New Delhi, India.
Rajesh AlogoluDepartment of Neurosurgery, Nizam's Institute of Medical Sciences, Hyderabad, Telangana, India.
Sagar GalwankarDepartment of Emergency Medicine, University of Florida Jacksonville, USA.
Saginela Satish KumarDepartment of Accident and Emergency Medicine, Narayana Medical College and Hospitals, Nellore, Andhra Pradesh, India.
Pathapati Rama MomhanDepartment of Pharmacology, Narayana Medical College and Hospitals, Nellore, Andhra Pradesh, India.
Ranabir PalDepartment of Community Medicine, Andaman and Nicobar Islands Institute of Medical Sciences, Port Blair - 744104, India.
Neeti RustagiDepartment of Community Medicine and Family Medicine, All India Institute of Medical Sciences, Jodhpur, Rajasthan, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimThis paper provides an overview of publications by Indian researchers on traumatic brain injury between 1966 and 2014, to set up a platform for evaluating and synthesizing the results and findings from brain injury research in India. MATERIALS AND

methodsAll published articles from India related to brain injury since 1966 to 2014 were retrieved from PubMed using the search for ("craniocerebral trauma"[MeSH Terms] OR ("craniocerebral"[All Fields] AND "trauma"[All Fields]) OR "craniocerebral trauma"[All Fields] OR ("head"[All Fields] AND "injury"[All Fields]) OR "head injury"[All Fields]) AND ("India"[MeSH Terms] OR "India"[All Fields]) A data base for variables like study type/category, year of publication, place of study institutes and departments to which the corresponding author belonged or where the study was conducted and the journal of publication was developed in FileMaker Pro 13 Advanced(®) software. Frequencies and percentages was obtained using R statistics software.

resultsA total of 624 original research articles from India were reviewed. There was a substantial increase in the number of publications from 2006 (175) to 2014 (213). Eighty percent of studies were primary clinical observational type. Only 1.6% of studies were on animal experiments. Original research articles were about 55.8%. One fourth of the studies are prospective in nature. Researchers from 46 medical departments have been involved in publishing papers on traumatic brain injury. Among these, the neurosurgery department has published highest number of publications (262), followed by the forensic medicine (32) and the neurology (21). Many institutes from 22 states have contributed in brain injury research. Delhi alone had published nearly one-fourth (23%) of papers. Eleven states had published papers in collaboration with other countries. Papers were published both in national and international journals. Neurology India had published 20.6% of papers.

conclusionThere is rapid increase in publications since last decade with multi departmental integration and international collaborations. However with existing brain injury resources in our country much more research work at both basic and clinical level should be encouraged.

Indexed as

Articlesbasicbrain injuryclinicaldepartmentsepidemiologicalIndiainstitutesjournalneurosurgeryneurotraumaPubMed

Identifiers

PMID27308253
PMCPMC4901829

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.