ArticleChemistryOpen2016
An Artificial Molecular Transporter.
Article in ChemistryOpen, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
8 citing papers in PubMed.
- Directional Macrocycle Transport, Release, and Recapture Enabled by a Rotaxane Transporter.Chemistry (Weinheim an der Bergstrasse, Germany) · 2025Article
- Photochemical Energy Conversion with Artificial Molecular Machines.Energy & fuels : an American Chemical Society journal · 2021Review
- Direct synthetic routes to functionalised crown ethers.Organic chemistry frontiers : an international journal of organic chemistry · 2021Review
- Artificial Supramolecular Pumps Powered by Light.Chemistry (Weinheim an der Bergstrasse, Germany) · 2021Article
- Electrochemically switchable rotaxanes: recent strides in new directions.Chemical science · 2019Review
- Photoactive Molecular-Based Devices, Machines and Materials: Recent Advances.European journal of inorganic chemistry · 2018Review
- Remote electrochemical modulation of pKProceedings of the National Academy of Sciences of the United States of America · 2018Article
- An Artificial Molecular Transporter.ChemistryOpen · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The transport of substrates is one of the main tasks of biomolecular machines in living organisms. We report a synthetic small-molecule system designed to catch, displace, and release molecular cargo in solution under external control. The system consists of a bistable rotaxane that behaves as an acid-base controlled molecular shuttle, whose ring component bears a tether ending with a nitrile group. The latter can be coordinated to a ruthenium complex that acts as the load, and dissociated upon irradiation with visible light. The cargo loading/unloading and ring transfer/return processes are reversible and can be controlled independently. The robust coordination bond ensures that the cargo remains attached to the device while the transport takes place.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.