Evidence map›Paper›PMID 27307782›Full record

ArticleThe South African journal of psychiatry : SAJP : the journal of the Society of Psychiatrists of South Africa

Substance use and duration of untreated psychosis in KwaZulu-Natal, South Africa.

Glen P Davis, Andrew Tomita, Joy Noel Baumgartner, Sisanda Mtshemla, Siphumelele Nene, Howard King, Ezra Susser, Jonathan K Burns

Open access · goldAbstract read
In one paragraph

Article in The South African journal of psychiatry : SAJP : the journal of the Society of Psychiatrists of South Africa. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 21 citations in OpenAlex.

  1. Changes in cannabis use post decriminalisation in mental health care users in South Africa.The South African journal of psychiatry : SAJP : the journal of the Society of Psychiatrists of South Africa · 2025
    Article
  2. Alcohol, Smoking and Substance Involvement Screening Test validity in bipolar and psychotic disorders.The South African journal of psychiatry : SAJP : the journal of the Society of Psychiatrists of South Africa · 2023
    Article
  3. Prevalence of cannabis use in people with psychosis in KwaZulu-Natal, South Africa.The South African journal of psychiatry : SAJP : the journal of the Society of Psychiatrists of South Africa · 2022
    Article
  4. Article
  5. Prevalence and clinical correlates of substance use amongst acute psychiatric inpatients in Gauteng, South Africa.The South African journal of psychiatry : SAJP : the journal of the Society of Psychiatrists of South Africa · 2020
    Article
  6. Article
  7. Factors associated with the successful completion of a substance rehabilitation programme at a psychiatric training hospital.The South African journal of psychiatry : SAJP : the journal of the Society of Psychiatrists of South Africa · 2020
    Article
  8. Article
  9. First-episode psychosis and substance use in Nelson Mandela Bay: Findings from an acute mental health unit.The South African journal of psychiatry : SAJP : the journal of the Society of Psychiatrists of South Africa · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Glen P DavisColumbia University Medical Center, Department of Psychiatry, New York, NY, United States of America.
Andrew TomitaUniversity of KwaZulu-Natal, Nelson R. Mandela School of Medicine, Durban, South Africa.
Joy Noel BaumgartnerDuke Global Health Institute, Duke University, Durham, NC, United States of America.
Sisanda MtshemlaUniversity of KwaZulu-Natal, Nelson R. Mandela School of Medicine, Durban, South Africa; KwaZulu-Natal Department of Health, Durban, South Africa.
Siphumelele NeneHealth Economics and HIV/AIDS Research Division (HEARD), University of KwaZulu-Natal, Durban, South Africa.
Howard KingUniversity of KwaZulu-Natal, Nelson R. Mandela School of Medicine, Durban, South Africa; KwaZulu-Natal Department of Health, Durban, South Africa.
Ezra SusserColumbia University Mailman School of Public Health, Department of Epidemiology, New York, NY, United States of America; New York State Psychiatric Institute, United States of America.
Jonathan K BurnsUniversity of KwaZulu-Natal, Nelson R. Mandela School of Medicine, Durban, South Africa; KwaZulu-Natal Department of Health, Durban, South Africa.
University of KwaZulu-Natal · ZAColumbia University Irving Medical Center · USDuke Institute for Health Innovation · USNew York State Psychiatric Institute

Funding

Fogarty International Clinical Research Scholars Support Center @ Vanderbilt-AAMCR24TW007988 · FIC · VANDERBILT UNIVERSITY · PI VERMUND, STEN H. · 2007 to 2011
$27.6M
RESEARCH TRAINING PROGRAM IN PSYCHIATRIC EPIDEMIOLOGYT32MH013043 · NIMH · COLUMBIA UNIV NEW YORK MORNINGSIDE · PI Katherine M. Keyes · 1985 to 2026
$11.7M
Translational Clinical Research Fellowship on Substance Use DisordersT32DA007294 · NIDA · COLUMBIA UNIV NEW YORK MORNINGSIDE · PI Frances Rudnick Levin, Diana M Martinez · 1993 to 2026
$9.3M
Vanderbilt-Emory-Cornell-Duke Consortium for Global Health Fellows (VECDor)R25TW009337 · FIC · VANDERBILT UNIVERSITY MEDICAL CENTER · PI HEIMBURGER, DOUGLAS CORBETT, VERMUND, STEN H. · 2012 to 2016
$6.3M
Psychotic disorders in an African setting: Incidence, early course, and treatmentR21MH093296 · NIMH · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI BURNS, JONATHAN, SUSSER, EZRA S. · 2011 to 2012
$284k
FIC NIH HHS R24 TW007988FIC NIH HHS R25 TW009337NIDA NIH HHS T32 DA007294NIMH NIH HHS R21 MH093296NIMH NIH HHS T32 MH013043
6 · The paper itself

Abstract

backgroundSubstance use and psychiatric disorders cause significant burden of disease in low- and middle-income countries. Co-morbid psychopathology and longer duration of untreated psychosis (DUP) can negatively affect treatment outcomes.

objectivesThe study assessed substance use amongst adults with severe mental illness receiving services at a regional psychiatric hospital in KwaZulu-Natal (South Africa). We describe the prevalence and correlates of lifetime substance use and examine the association between substance use and DUP.

methodsA cross-sectional survey recruited adults diagnosed with severe mental illness and assessed lifetime and past 3-month substance use using the World Health Organization Alcohol, Smoking and Substance Involvement Screening Test. Regression analyses were conducted to determine associations between lifetime substance use (other than alcohol and tobacco) and DUP as measured by the World Health Organization Encounter Form.

resultsAmongst 87 participants, alcohol (81.6%), tobacco (75.6%) and cannabis (49.4%) were the most common substances reported for lifetime use. Risk of health-related problems (health, social, financial, legal and relationship) of cannabis use was associated with younger age, single marital status and lower education. Adjusted regression analyses indicated that use of amphetamines and methaqualone is associated with longer DUP.

conclusionsSubstance use is prevalent amongst psychiatric patients in KwaZulu-Natal and may contribute to longer DUP. Mental health services in this region should address co-morbid substance use and psychiatric disorders.

Identifiers

PMID27307782
PMCPMC4904841
OpenAlexW2408194303

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.