ReviewOpen access emergency medicine : OAEM2016
Clinical decision rules for acute bacterial meningitis: current insights.
Review in Open access emergency medicine : OAEM, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
16 citing papers in PubMed.
- Lumbar Puncture and Brain Herniation in Acute Bacterial Meningitis: An Updated Narrative Review.Journal of intensive care medicine · 2026Review
- Utility and performance of cerebrospinal fluid cytology in discriminating central nervous system infections and brain tumors.Journal of neuro-oncology · 2025Article
- Early detection of cerebrospinal fluid/serum glucose ratio: A promising value for mortality prognosis in patients with acute bacterial meningitis.Journal of general and family medicine · 2025Article
- The Diagnostic Utility of Cerebrospinal Fluid Procalcitonin for Acute Bacterial Meningitis and Ventriculitis in Children: A Multicenter Prospective Study.Acta medica Philippina · 2025Article
- Bacterial Meningitis Following Aneurysmal Subarachnoid Hemorrhage and Its Association with Cerebral Vasospasm.Neurologia medico-chirurgica · 2024Article
- Clinical significance of cerebrospinal fluid presepsin as adjunctive biomarker for postneurosurgical meningitis: A single-center prospective observational study.Surgical neurology international · 2024Article
- Population Pharmacokinetic Modeling and Probability of Target Attainment of Ceftaroline in Brain and Soft Tissues.Antimicrobial agents and chemotherapy · 2022Article
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- Frequency of etiological agents of acute bacterial meningitis using culture and polymerase chain reaction assay.New microbes and new infections · 2021Article
- Infectious Complications of Expanded Endoscopic Transsphenoidal Surgery: A Retrospective Cohort Analysis of 100 Cases.Journal of neurological surgery. Part B, Skull base · 2020Article
- Toll-like receptor linked cytokine profiles in cerebrospinal fluid discriminate neurological infection from sterile inflammation.Brain communications · 2020Article
- Diagnostic Approach to Health Care- and Device-Associated Central Nervous System Infections.Journal of clinical microbiology · 2018Review
- The Role of Procalcitonin in the Diagnosis of Meningitis: A Literature Review.Journal of clinical medicine · 2018Review
- Cerebrospinal Fluid Presepsin As a Marker of Nosocomial Infections of the Central Nervous System: A Prospective Observational Study.Frontiers in neurology · 2018Article
- Chemical meningitis related to intra-CSF liposomal cytarabine.CNS oncology · 2017Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Acute community-acquired bacterial meningitis (BM) requires rapid diagnosis so that suitable treatment can be instituted within 60 minutes of admitting the patient. The cornerstone of diagnostic examination is lumbar puncture, which enables microbiological analysis and determination of the cerebrospinal fluid (CSF) cytochemical characteristics. However, microbiological testing is not sufficiently sensitive to rule out this diagnosis. With regard to the analysis of standard CSF cytochemical characteristics (polymorphonuclear count, CSF glucose and protein concentration, and CSF:serum glucose), this is often misleading. Indeed, the relatively imprecise nature of the cutoff values for these BM diagnosis markers can make their interpretation difficult. However, there are two markers that appear to be more efficient than the standard ones: CSF lactate and serum procalcitonin levels. Scores and predictive models are also available; however, they only define a clinical probability, and in addition, their use calls for prior validation on the population in which they are used. In this article, we review current methods of BM diagnosis.
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