Evidence map›Paper›PMID 27307460›Full record

ArticleJournal of clinical microbiology2016

Mycoplasma genitalium Prevalence, Coinfection, and Macrolide Antibiotic Resistance Frequency in a Multicenter Clinical Study Cohort in the United States.

Damon Getman, Alice Jiang, Meghan O'Donnell, Seth Cohen

Open access · hybridAbstract readClinical StudyMulticenter Study
In one paragraph

Article in Journal of clinical microbiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 77 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
77citing papers in PubMed, 2 pooled it
15.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

77 citing papers in PubMed, 2 syntheses or guidelines pooled it, 172 citations in OpenAlex.

  1. German evidence- and consensus-based guideline on the management of penile urethritis.Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG · 2025
    Guideline
  2. Guideline
  3. Trial
  4. Mycoplasma genitalium Infection in Kenyan and US Women.Sexually transmitted diseases · 2018
    Trial
  5. Article
  6. Trends and Themes inOpen forum infectious diseases · 2026
    Article
  7. Article
  8. Spread of dual-class drug-resistantAntimicrobial agents and chemotherapy · 2026
    Article
  9. Article
  10. Article
  11. Review
  12. Tropical medicine and infectious disease · 2025
    Article
  13. Article
  14. To Screen or Not to Screen-Controversies in Testing forJournal of the Association of Medical Microbiology and Infectious Disease Canada = Journal officiel de l'Association pour la microbiologie medicale et l'infectiologie Canada · 2024
    Article
  15. Article
  16. Article
  17. Le infezioni in medicina · 2024
    Article
  18. Mycoplasma genitalium in the US (MyGeniUS): Surveillance Data From Sexual Health Clinics in 4 US Regions.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2023
    Article
  19. Canada communicable disease report = Releve des maladies transmissibles au Canada · 2023
    Article
  20. Article

17 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Damon GetmanHologic, Inc., San Diego, California, USA damon.getman@hologic.com.
Alice JiangHologic, Inc., San Diego, California, USA.
Meghan O'DonnellHologic, Inc., San Diego, California, USA.
Seth CohenOccidental College, Los Angeles, California, USA.
Hologic (United States) · USOccidental College · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The prevalence rates of Mycoplasma genitalium infections and coinfections with other sexually transmitted organisms and the frequency of a macrolide antibiotic resistance phenotype were determined in urogenital specimens collected from female and male subjects enrolled in a multicenter clinical study in the United States. Specimens from 946 subjects seeking care from seven geographically diverse clinical sites were tested for M. genitalium and for Chlamydia trachomatis, Neisseria gonorrhoeae, and Trichomonas vaginalis Sequencing was used to assess macrolide antibiotic resistance among M. genitalium-positive subjects. M. genitalium prevalence rates were 16.1% for females and 17.2% for males. Significant risk factors for M. genitalium infections were black race, younger age, non-Hispanic ethnicity, and female symptomatic status. Female M. genitalium infections were significantly more prevalent than C. trachomatis and N. gonorrhoeae infections, while the M. genitalium infection rate in males was significantly higher than the N. gonorrhoeae and T. vaginalis infection rates. The macrolide-resistant phenotype was found in 50.8% of females and 42% of males. These results show a high prevalence of M. genitalium single infections, a lower prevalence of coinfections with other sexually transmitted organisms, and high rates of macrolide antibiotic resistance in a diverse sample of subjects seeking care across a wide geographic area of the United States.

Indexed as

Drug Resistance, BacterialAdolescentAdultAgedAnti-Bacterial AgentsChlamydia trachomatisCoinfectionFemaleHumansMacrolidesMaleMiddle AgedMycoplasma genitaliumMycoplasma InfectionsNeisseria gonorrhoeaePrevalenceAnti-Bacterial AgentsMacrolides

Identifiers

PMID27307460
PMCPMC5005488
OpenAlexW2508614923

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.