ArticleHypertension research : official journal of the Japanese Society of Hypertension2016
Increased neuronal seizure activity correlates with excessive systemic inflammation in a rat model of severe preeclampsia.
Article in Hypertension research : official journal of the Japanese Society of Hypertension, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 21 citations in OpenAlex.
- The neuro-immune axis in preeclampsia: from the maternal-fetal interface to systemic dysregulation.Frontiers in immunology · 2026Review
- MRI characteristics of brain edema in preeclampsia/eclampsia patients with posterior reversible encephalopathy syndrome.BMC pregnancy and childbirth · 2021Article
- Prenatal intake of omega-3 promotes Wnt/β-catenin signaling pathway, and preserves integrity of the blood-brain barrier in preeclamptic rats.Physiological reports · 2021Article
- Nicotine Alleviates Cortical Neuronal Injury by Suppressing Neuroinflammation and Upregulating Neuronal PI3K-AKT Signaling in an Eclampsia-Like Seizure Model.Neurotoxicity research · 2020Article
- Cyclosporin A ameliorates eclampsia seizure through reducing systemic inflammation in an eclampsia-like rat model.Hypertension research : official journal of the Japanese Society of Hypertension · 2020Article
- Targeting inflammation to reduce seizure severity in an experimental model of eclampsia.Hypertension research : official journal of the Japanese Society of Hypertension · 2020Article
- Neuroimaging findings in women who develop neurologic symptoms in severe preeclampsia with or without eclampsia.Hypertension research : official journal of the Japanese Society of Hypertension · 2018Article
- Effect of blood pressure on reversible posterior leukoencephalopathy syndrome in pre-eclampsia or eclampsia.Hypertension research : official journal of the Japanese Society of Hypertension · 2018Article
- Changes in the Expression of AQP4 and AQP9 in the Hippocampus Following Eclampsia-Like Seizure.International journal of molecular sciences · 2018Article
- Magnesium Sulfate Provides Neuroprotection in Eclampsia-Like Seizure Model by Ameliorating Neuroinflammation and Brain Edema.Molecular neurobiology · 2017Article
- Description of a strong relationship among total cell-free DNA levels, LDH values, AST values and platelet count in patients with HELLP syndrome.Hypertension research : official journal of the Japanese Society of Hypertension · 2017Article
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Preeclampsia (PE), one of the most common disorders of pregnancy, is characterized by hypertension and albuminuria. In severe cases, PE results in eclampsia-like seizures. Studies have suggested that severe PE is related to an exaggerated systemic inflammatory response, which may increase sensitivity to seizures. In the current study, we investigated whether the seizure activity of neurons was enhanced under excessive systemic inflammation. We also sought to determine whether MgSO
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