Regulatory T Cell Therapy for Ischemic Stroke: how far from Clinical Translation?

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

21 citing papers in PubMed, 39 citations in OpenAlex.

1. Regulatory T cells in stroke inflammation: Therapeutic perspectives.Neural regeneration research · 2026
   Article
2. The role of miRNAs in the development of Super-Tregs as a potential therapy for neurodegenerative diseases.Frontiers in immunology · 2026
   Review
3. Regulatory T Cells for Stroke Recovery: A Promising Immune Therapeutic Strategy.CNS neuroscience & therapeutics · 2025
   Review
4. GPR55 Inactivation Diminishes Splenic Responses and Improves Neurological Outcomes in the Mouse Ischemia/Reperfusion Stroke Model.Cells · 2024
   Article
5. Neuroinflammation and anti-inflammatory therapy for ischemic stroke.Heliyon · 2023
   Review
6. Engineering of Immune Microenvironment for Enhanced Tissue Remodeling.Tissue engineering and regenerative medicine · 2022
   Review
7. Regulatory T cells in ischemic stroke.Acta pharmacologica Sinica · 2022
   Review
8. IL-2/IL-2R Antibody Complex Enhances Treg-Induced Neuroprotection by Dampening TNF-α Inflammation in an In Vitro Stroke Model.Neuromolecular medicine · 2021
   Article
9. The effect of fingolimod on regulatory T cells in a mouse model of brain ischaemia.Journal of neuroinflammation · 2021
   Article
10. The immune response of T cells and therapeutic targets related to regulating the levels of T helper cells after ischaemic stroke.Journal of neuroinflammation · 2021
    Review
11. Mechanisms in blood-brain barrier opening and metabolism-challenged cerebrovascular ischemia with emphasis on ischemic stroke.Metabolic brain disease · 2020
    Review
12. Harnessing regulatory T cell neuroprotective activities for treatment of neurodegenerative disorders.Molecular neurodegeneration · 2020
    Review
13. Regulatory T-cells within bone marrow-derived stem cells actively confer immunomodulatory and neuroprotective effects against stroke.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2019
    Article
14. Transplanting Mesenchymal Stem Cells for Treatment of Ischemic Stroke.Cell transplantation · 2018
    Review
15. Vinpocetine Inhibits NF-κB-Dependent Inflammation in Acute Ischemic Stroke Patients.Translational stroke research · 2018
    Article
16. Regenerative Medicine Therapies for Targeting Neuroinflammation After Stroke.Frontiers in neurology · 2018
    Review
17. The role of regulatory T cells in the regulation of upper airway inflammation.American journal of rhinology & allergy · 2017
    Article
18. Correcting the Trajectory of Stroke Therapeutic Research.Translational stroke research · 2017
    Article
19. Neuroprotective Effects of Stem Cells in Ischemic Stroke.Stem cells international · 2017
    Review
20. BMP4/LIF or RA/Forskolin Suppresses the Proliferation of Neural Stem Cells Derived from Adult Monkey Brain.Stem cells international · 2017
    Article

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

Authors and funding

4 authors at 1 institution in 1 country.

Funding

Abstract

PubMed holds no abstract for this paper.

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