Trial reportBritish journal of sports medicine2016
Analysis of head impact exposure and brain microstructure response in a season-long application of a jugular vein compression collar: a prospective, neuroimaging investigation in American football.
Trial report in British journal of sports medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 26 papers, 4 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Novel Protection Against Potential Brain Injury During Competitive Football Head Impacts
The Use of Q-Collar to Increase CSF Drainage in Low-pressure Hydrocephalus Patients
Who cites it
26 citing papers in PubMed, 4 syntheses or guidelines pooled it, 84 citations in OpenAlex.
- Head Impact Research Using Inertial Sensors in Sport: A Systematic Review of Methods, Demographics, and Factors Contributing to Exposure.Sports medicine (Auckland, N.Z.) · 2022Pooled it
- The accumulation of subconcussive impacts on cognitive, imaging, and biomarker outcomes in child and college-aged athletes: a systematic review.Brain imaging and behavior · 2022Pooled it
- Injury Profile in Women's Football: A Systematic Review and Meta-Analysis.Sports medicine (Auckland, N.Z.) · 2021Pooled it
- The second decade of DTI in TBI part 1: a systematic review of mild TBI.Frontiers in neurologyPooled it
- Influence of a neck compression collar on cerebrovascular and autonomic function in men and women.PloS one · 2019Trial
- Mild Jugular Compression Collar Ameliorated Changes in Brain Activation of Working Memory after One Soccer Season in Female High School Athletes.Journal of neurotrauma · 2018Trial
- Bidirectional mechanisms and emerging strategies for implantable bioelectronic interfaces.Bioactive materials · 2025Review
- Correlating Magnetoencephalography, Diffusion Kurtosis Imaging, Biomechanics, and Neuropsychology in American Youth Football.Journal of neurotrauma · 2025Article
- Effects of neck compression on chemoreflex sensitivity and cardiorespiratory hemodynamics in patients with postural orthostatic tachycardia syndrome (POTS).Clinical autonomic research : official journal of the Clinical Autonomic Research Society · 2025Article
- Associations Between Brain Metabolites Measured With MR Spectroscopy and Head Impacts in High School American Football Athletes.Journal of magnetic resonance imaging : JMRI · 2025Article
- Beyond the Hit: The Hidden Costs of Repetitive Head Trauma.Neuroscience insights · 2025Review
- Review
- Review
- Helmet Technology, Head Impact Exposure, and Cortical Thinning Following a Season of High School Football.Annals of biomedical engineering · 2022Article
- Altered white matter diffusivity and subtle motor function in a pilot cohort of adolescents with sports-related concussion.Brain injury · 2022Article
- Evaluation of the Effectiveness of Newer Helmet Designs with Emergent Shell and Padding Technologies Versus Older Helmet Models for Preserving White Matter Following a Season of High School Football.Annals of biomedical engineering · 2021Article
- The Effects of On-Field Heat Index and Altitude on Concussion Assessments and Recovery Among NCAA Athletes.Sports medicine (Auckland, N.Z.) · 2021Article
- Development of brain atlases for early-to-middle adolescent collision-sport athletes.Scientific reports · 2021Article
- Changes in White Matter of the Cervical Spinal Cord after a Single Season of Collegiate Football.Neurotrauma reports · 2021Article
- Concussion in soccer: a comprehensive review of the literature.Concussion (London, England) · 2020Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
15 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundHistorical approaches to protect the brain from outside the skull (eg, helmets and mouthpieces) have been ineffective in reducing internal injury to the brain that arises from energy absorption during sports-related collisions. We aimed to evaluate the effects of a neck collar, which applies gentle bilateral jugular vein compression, resulting in cerebral venous engorgement to reduce head impact energy absorption during collision. Specifically, we investigated the effect of collar wearing during head impact exposure on brain microstructure integrity following a competitive high school American football season.
methodsA prospective longitudinal controlled trial was employed to evaluate the effects of collar wearing (n=32) relative to controls (CTRL; n=30) during one competitive football season (age: 17.04±0.67 years). Impact exposure was collected using helmet sensors and white matter (WM) integrity was quantified based on diffusion tensor imaging (DTI) serving as the primary outcome.
resultsWith similar overall g-forces and total head impact exposure experienced in the two study groups during the season (p>0.05), significant preseason to postseason changes in mean diffusivity, axial diffusivity and radial diffusivity in the WM integrity were noted in the CTRL group (corrected p<0.05) but not in the collar group (p>0.05). The CTRL group demonstrated significantly larger preseason to postseason DTI change in multiple WM regions compared with the collar group (corrected p<0.05). DISCUSSION: Reduced WM diffusivity alteration was noted in participants wearing a neck collar after a season of competitive football. Collar wearing may have provided a protective effect against brain microstructural changes after repetitive head impacts. TRIAL REGISTRATION NUMBER: NCT02696200.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.