ArticleCommunity mental health journal2016
Comorbid Moderate-Severe Depressive Symptoms and their Association with Quality of Life in Chinese Patients with Schizophrenia Treated in Primary Care.
Article in Community mental health journal, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed.
- Gender-specific correlates for suicide mortality in people with schizophrenia: a 9-year population-based study.BMC psychiatry · 2024Article
- Subjective quality of life and schizophrenia: results from a large cohort study based in Chinese primary care.BMC psychiatry · 2024Article
- Enhanced computerized cognitive remediation therapy improved cognitive function, negative symptoms, and GDNF in male long-term inpatients with schizophrenia.Frontiers in psychiatry · 2024Article
- Rumination mediates the relationship between childhood trauma and depressive symptoms in schizophrenia patients.European archives of psychiatry and clinical neuroscience · 2023Article
- Quality of life in patients with schizophrenia: A 2-year cohort study in primary mental health care in rural China.Frontiers in public health · 2022Article
- Gender Differences of Schizophrenia Patients With and Without Depressive Symptoms in Clinical Characteristics.Frontiers in psychiatry · 2021Article
- Phenome-wide and genome-wide analyses of quality of life in schizophrenia.BJPsych open · 2020Article
- The Mediating Effect of Depression and Disability in the Relationship Between Schizophreniaand Self-Esteem.The Psychiatric quarterly · 2020Article
- The clinical course of schizophrenia in women and men-a nation-wide cohort study.NPJ schizophrenia · 2020Article
- The prevalence and associated factors of depression among patients with schizophrenia in Addis Ababa, Ethiopia, cross-sectional study.BMC psychiatry · 2020Article
- Rethinking Schizophrenia and Depression Comorbidity as One Psychiatric Disorder Entity: Evidence From Mouse Model.Frontiers in neuroscience · 2020Article
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Authors and funding
13 authors.
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Abstract
This study described the prevalence and correlates of comorbid moderate-severe depressive symptoms (comorbid depression thereafter) and their association with quality of life (QOL) in schizophrenia patients treated in primary care. 623 schizophrenia patients were enrolled. Patients' socio-demographic and clinical characteristics including comorbid depression [defined as a total score of 18 or above on the Montgomery-Asberg Depression Rating Scale (MADRS)] were recorded. Depressive symptoms (defined as a total score of 9 or above on the MADRS) were present in 54.1 % of patients, while 17.7 % had comorbid depression. Analysis of covariance revealed that comorbid depression was significantly associated with lower mental QOL. Multiple logistic regression analysis revealed that more severe positive and negative symptoms, anxiety symptoms, use of first-generation antipsychotics and antidepressants, were independently associated with comorbid depression. Given the negative association between comorbid depression and QOL, attempts to address comorbid depression in schizophrenia patients treated in primary care should be made.
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