ArticleScientific reports2016
Heat shock protein 90 is required for sexual and asexual development, virulence, and heat shock response in Fusarium graminearum.
Article in Scientific reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
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Who cites it
27 citing papers in PubMed, 54 citations in OpenAlex.
- Impacts of climate extremes on plant pathogens, microbiomes and plant health.Nature reviews. Microbiology · 2026Review
- Differential gene expression to heat stress drives thermotolerance, pathogenicity, and reproduction in Fusarium head blight pathogens: from transcriptomic profiling to functional validation.BMC plant biology · 2026Article
- GSK3 phosphorylates and activates trehalose-6-phosphate synthase to improve trehalose production and thermotolerance in Ganoderma lucidum.Communications biology · 2025Article
- A 3DmSphere · 2025Article
- Morphological and Transcriptomic Response Mediated by Heat Stress in Pleurotus Pulmonarius.Current microbiology · 2025Article
- UV-Induced Mutants ofJournal of fungi (Basel, Switzerland) · 2025Article
- Review
- Genomic Sequencing and Functional Analysis of the Ex-Type Strain ofJournal of fungi (Basel, Switzerland) · 2024Article
- Comparative Transcriptomic Analyses Propose the Molecular Regulatory Mechanisms Underlying 1,8-Cineole fromMolecules (Basel, Switzerland) · 2023Review
- A combined transcriptomic and physiological approach to understanding the adaptive mechanisms to cope with oxidative stress inMicrobiology spectrum · 2023Article
- UDP-Galactopyranose Mutase Mediates Cell Wall Integrity, Polarity Growth, and Virulence in Fusarium graminearum.Applied and environmental microbiology · 2023Article
- Comparative Proteomic Analysis ofJournal of fungi (Basel, Switzerland) · 2022Article
- Fungal communities represent the majority of root-specific transcripts in the transcriptomes ofPeerJ · 2022Article
- Key infection stages defending heat stress in high-temperature-resistantFrontiers in microbiology · 2022Article
- Construction of a heat-resistant strain ofFrontiers in microbiology · 2022Article
- Development of a versatile copper-responsive gene expression system in the plant-pathogenic fungus Fusarium graminearum.Molecular plant pathology · 2021Article
- Functional Roles of αApplied and environmental microbiology · 2021Article
- Effect of H2A.Z deletion is rescued by compensatory mutations in Fusarium graminearum.PLoS genetics · 2020Article
- Systematic Analysis of Lysine Lactylation in the Plant Fungal PathogenFrontiers in microbiology · 2020Article
- Chronic Sublethal Aluminum Exposure andFrontiers in microbiology · 2020Article
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Authors and funding
8 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Eukaryotic cells repress global translation and selectively upregulate stress response proteins by altering multiple steps in gene expression. In this study, genome-wide transcriptome analysis of cellular adaptation to thermal stress was performed on the plant pathogenic fungus Fusarium graminearum. The results revealed that profound alterations in gene expression were required for heat shock responses in F. graminearum. Among these proteins, heat shock protein 90 (FgHsp90) was revealed to play a central role in heat shock stress responses in this fungus. FgHsp90 was highly expressed and exclusively localised to nuclei in response to heat stress. Moreover, our comprehensive functional characterisation of FgHsp90 provides clear genetic evidence supporting its crucial roles in the vegetative growth, reproduction, and virulence of F. graminearum. In particular, FgHsp90 performs multiple functions as a transcriptional regulator of conidiation. Our findings provide new insight into the mechanisms underlying adaptation to heat shock and the roles of Hsp90 in fungal development.
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