Evidence map›Paper›PMID 27306415›Full record

ArticleJournal of biomechanical engineering2016

Repeated Loading Behavior of Pediatric Porcine Common Carotid Arteries.

Stephanie A Pasquesi, Yishan Liu, Susan S Margulies

Open access · bronzeAbstract read
In one paragraph

Article in Journal of biomechanical engineering, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 9 citations in OpenAlex.

  1. Trial
  2. Stress-Relaxation and Cyclic Behavior of Human Carotid Plaque Tissue.Frontiers in bioengineering and biotechnology · 2020
    Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Stephanie A PasquesiDepartment of Bioengineering, University of Pennsylvania, 240 Skirkanich Hall, 210 South 33rd Street, Philadelphia, PA 19104-6321.
Yishan LiuDepartment of Bioengineering, University of Pennsylvania, 240 Skirkanich Hall, 210 South 33rd Street, Philadelphia, PA 19104-6321.
Susan S MarguliesDepartment of Bioengineering, University of Pennsylvania, 240 Skirkanich Hall, 210 South 33rd Street, Philadelphia, PA 19104-6321 e-mail: margulie@seas.upenn.edu.
University of Pennsylvania · US

Funding

PRECLINICAL CYCLOSPORIN A THERAPY TRIALS FOR PEDIATRIC TBIU01NS069545 · NINDS · UNIVERSITY OF PENNSYLVANIA · PI DUHAIME, ANN-CHRISTINE, MARGULIES, SUSAN SHEPS · 2011 to 2017
$3.5M
Traumatic Bridging Vein Failure in InfantsR21HD078842 · NICHD · UNIVERSITY OF PENNSYLVANIA · PI MARGULIES, SUSAN SHEPS · 2014 to 2015
$424k
NICHD NIH HHS R21 HD078842NINDS NIH HHS U01 NS069545
6 · The paper itself

Abstract

Rapid flexion and extension of the neck may occur during scenarios associated with traumatic brain injury (TBI), and understanding the mechanical response of the common carotid artery (CCA) to longitudinal stretch may enhance understanding of contributing factors that may influence CCA vasospasm and exacerbate ischemic injury associated with TBI. Immature (4-week-old) porcine CCAs were tested under subcatastrophic (1.5 peak stretch ratio) cyclic loading at 3 Hz for 30 s. Under subcatastrophic cyclic longitudinal extension, the immature porcine CCA displays softening behavior. This softening can be represented by decreasing peak stress and increasing corner stretch values with an increasing number of loading cycles. This investigation is an important first step in the exploration of fatiguelike behavior in arterial tissue that may be subjected to repeated longitudinal loads.

Indexed as

Models, CardiovascularPhysical StimulationAnimalsAnisotropyCarotid Artery, CommonComputer SimulationElastic ModulusHardnessIn Vitro TechniquesStress, MechanicalSwineTensile Strength

Identifiers

PMID27306415
PMCPMC5125306
OpenAlexW2431523527

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.