ArticleJournal of biomechanical engineering2016
A Combined Experimental and Computational Approach to Subject-Specific Analysis of Knee Joint Laxity.
Article in Journal of biomechanical engineering, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
32 citing papers in PubMed.
- Comparison of Marker-Based and Stereo Radiography Knee Kinematics in Activities of Daily Living.Annals of biomedical engineering · 2018Trial
- Deciphering the "Art" in Modeling and Simulation of the Knee Joint: Model Benchmarking.Journal of biomechanical engineering · 2026Article
- Strategy to step on obstacle during cross-country race to minimize overuse injury risk.PloS one · 2026Article
- Computational Dynamic Analysis of Medial Meniscus with Redial Tear, Repair, and Meniscectomy.Annals of biomedical engineering · 2025Article
- Validating subject-specific knee models fromFrontiers in bioengineering and biotechnology · 2025Article
- Efficient development of subject-specific finite element knee models: Automated identification of soft-tissue attachments.Journal of biomechanics · 2025Article
- Tailored Multibody Tibiofemoral Joint Model for Precision Care.Applied bionics and biomechanics · 2025Article
- Influence of the Initial Guess on the Estimation of Knee Ligament Parameters via Optimization Procedures.Bioengineering (Basel, Switzerland) · 2024Article
- In Vitro Assessment of Knee Joint Biomechanics Using a Virtual Anterior Cruciate Ligament Reconstruction.Journal of biomechanical engineering · 2024Article
- Computational study of extrinsic factors affecting ACL strain during single-leg jump landing.BMC musculoskeletal disorders · 2024Article
- Evaluation of machine learning techniques for real-time prediction of implanted lower limb mechanics.Frontiers in bioengineering and biotechnology · 2024Article
- Deciphering the "Art" in Modeling and Simulation of the Knee Joint: Assessing Model Calibration Workflows and Outcomes.Journal of biomechanical engineering · 2023Article
- Bayesian Calibration of Computational Knee Models to Estimate Subject-Specific Ligament Properties, Tibiofemoral Kinematics, and Anterior Cruciate Ligament Force With Uncertainty Quantification.Journal of biomechanical engineering · 2023Article
- Anatomical Tissue Engineering of the Anterior Cruciate Ligament Entheses.International journal of molecular sciences · 2023Review
- Photobiomodulation for knee osteoarthritis: a model-based dosimetry study.Biomedical optics express · 2023Article
- Assessment of reporting practices and reproducibility potential of a cohort of published studies in computational knee biomechanics.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2023Article
- Modeling of active skeletal muscles: a 3D continuum approach incorporating multiple muscle interactions.Frontiers in bioengineering and biotechnology · 2023Article
- Magnetic Resonance Imaging Versus Computed Tomography for Three-Dimensional Bone Imaging of Musculoskeletal Pathologies: A Review.Journal of magnetic resonance imaging : JMRI · 2022Review
- Robust automatic hexahedral cartilage meshing framework enables population-based computational studies of the knee.Frontiers in bioengineering and biotechnology · 2022Article
- A Parameter Sensitivity Analysis on Multiple Finite Element Knee Joint Models.Frontiers in bioengineering and biotechnology · 2022Article
Corrections and comments
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Authors and funding
7 authors.
Funding
Abstract
Modeling complex knee biomechanics is a continual challenge, which has resulted in many models of varying levels of quality, complexity, and validation. Beyond modeling healthy knees, accurately mimicking pathologic knee mechanics, such as after cruciate rupture or meniscectomy, is difficult. Experimental tests of knee laxity can provide important information about ligament engagement and overall contributions to knee stability for development of subject-specific models to accurately simulate knee motion and loading. Our objective was to provide combined experimental tests and finite-element (FE) models of natural knee laxity that are subject-specific, have one-to-one experiment to model calibration, simulate ligament engagement in agreement with literature, and are adaptable for a variety of biomechanical investigations (e.g., cartilage contact, ligament strain, in vivo kinematics). Calibration involved perturbing ligament stiffness, initial ligament strain, and attachment location until model-predicted kinematics and ligament engagement matched experimental reports. Errors between model-predicted and experimental kinematics averaged <2 deg during varus-valgus (VV) rotations, <6 deg during internal-external (IE) rotations, and <3 mm of translation during anterior-posterior (AP) displacements. Engagement of the individual ligaments agreed with literature descriptions. These results demonstrate the ability of our constraint models to be customized for multiple individuals and simultaneously call attention to the need to verify that ligament engagement is in good general agreement with literature. To facilitate further investigations of subject-specific or population based knee joint biomechanics, data collected during the experimental and modeling phases of this study are available for download by the research community.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.