Evidence map›Paper›PMID 27306120›Full record

ArticleFuture oncology (London, England)2016

Serum calcium, albumin and tumor stage in cutaneous malignant melanoma.

Mridul Datta, Paul Savage, James Lovato, Gary G Schwartz

Open access · greenAbstract read
In one paragraph

Article in Future oncology (London, England), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
0.7field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. The Role of Calcium Signaling in Melanoma.International journal of molecular sciences · 2022
    Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Mridul DattaPurdue University, West Lafayette, IN, USA.
Paul SavageWake Forest School of Medicine, Winston-Salem, NC, USA.
James LovatoWake Forest School of Medicine, Winston-Salem, NC, USA.
Gary G SchwartzUniversity of North Dakota School of Medicine & Health Sciences, 501 N Columbia Rd Stop 9037, Grand Forks, ND 25202-9037, USA.
Wake Forest University · USPurdue University West Lafayette · USUniversity of North Dakota · US

Funding

Tumor Tissue CoreP30CA012197 · NCI · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI Ruben A. Mesa · 1985 to 2026
$55.4M
Postdoctoral Training Program in Cancer SurvivorshipR25CA122061 · NCI · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI AVIS, NANCY E · 2008 to 2018
$3.8M
NCI NIH HHS P30 CA012197NCI NIH HHS R25 CA122061
6 · The paper itself

Abstract

aimAssess the relationship of serum calcium and serum albumin to tumor stage and other clinical characteristics in patients with cutaneous malignant melanoma (MM). PATIENTS &

methodsA cross-sectional study to evaluate serum calcium as a marker of disease progression (n = 644) in MM.

resultsSerum albumin was significantly lower among men (p < 0.01) and among patients with stage 4 disease (p < 0.05). In a multivariable regression model adjusted for age, gender and site, albumin-corrected calcium was positively associated with disease stage (odds ratio: 1.46; 95% CI: 1.02-2.07; p = 0.04). The odds of higher stage increased 60% for each 1.0 mg/dl increase in albumin-corrected calcium.

conclusionHigher albumin-corrected serum calcium may be a marker of disease progression in MM.

Indexed as

Serum AlbuminAgedBiomarkersCalciumCross-Sectional StudiesCutaneous Malignant MelanomaFemaleHumansMaleMelanomaMiddle AgedNeoplasm StagingPrognosisSkin NeoplasmsBiomarkersCalciumSerum Albuminalbuminalbumin-corrected calciummalignant melanomaserum calcium

Identifiers

PMID27306120
PMCPMC5066137
OpenAlexW2435420576

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.