ArticleMolecular & cellular oncology
Ribosome heterogeneity in tumorigenesis: the rRNA point of view.
Article in Molecular & cellular oncology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.
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Who cites it
30 citing papers in PubMed.
- Article
- Ribosome biogenesis and selective translational control as oncogenic vulnerabilities in hematologic malignancies.Molecular cancer · 2026Review
- Elevated NPM1 and FBL expression correlates with prostate cancer aggressiveness and progression.The Journal of pathology · 2025Article
- The structure of the human 80S ribosome at 1.9 Å resolution reveals the molecular role of chemical modifications and ions in RNA.Nature structural & molecular biology · 2024Article
- Heterogeneity of chemical modifications on RNA.Biophysical reviews · 2024Review
- Isocitrate dehydrogenase wt and IDHmut adult-type diffuse gliomas display distinct alterations in ribosome biogenesis and 2'O-methylation of ribosomal RNA.Neuro-oncology · 2023Article
- Hub genes identification and association of key pathways with hypoxia in cancer cells: A bioinformatics analysis.Saudi journal of biological sciences · 2023Article
- Review
- Review
- Ribosome-Directed Therapies in Cancer.Biomedicines · 2022Review
- Post-transcriptional diversity in riboproteins and RNAs in aging and cancer.Seminars in cancer biology · 2021Review
- The role of OncoSnoRNAs and Ribosomal RNA 2'-O-methylation in Cancer.RNA biology · 2021Review
- Regulation of ribosomal protein genes: An ordered anarchy.Wiley interdisciplinary reviews. RNA · 2021Review
- Nucleolar protein 10 (NOP10) predicts poor prognosis in invasive breast cancer.Breast cancer research and treatment · 2021Article
- Expansion segments in bacterial and archaeal 5S ribosomal RNAs.RNA (New York, N.Y.) · 2021Article
- snoRNAs Offer Novel Insight and Promising Perspectives for Lung Cancer Understanding and Management.Cells · 2020Review
- Review
- Landscape of NFrontiers in oncology · 2020Article
- NOL12 Repression Induces Nucleolar Stress-Driven Cellular Senescence and Is Associated with Normative Aging.Molecular and cellular biology · 2019Article
- Alteration of 28S rRNA 2'-Biology open · 2019Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The "specialized ribosome" concept proposes that ribosome variants are produced and differentially regulate translation. Examples supporting this notion demonstrated heterogeneity of ribosomal protein composition. However, ribosome translational activity is carried out by rRNA. We, and others, recently showed that rRNA heterogeneity regulates translation to generate distinct translatomes promoting tumorigenesis.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.