Evidence map›Paper›PMID 27304096›Full record

ArticleMemorias do Instituto Oswaldo Cruz2016

Candida duobushaemulonii: an emerging rare pathogenic yeast isolated from recurrent vulvovaginal candidiasis in Brazil.

Humberto Fabio Boatto, Sarah Desirée Barbosa Cavalcanti, Gilda Mb Del Negro, Manoel João Bc Girão, Elaine Cristina Francisco, Kelly Ishida, Olga Fischman Gompertz

Abstract read
In one paragraph

Article in Memorias do Instituto Oswaldo Cruz, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Article
  2. Silent Outbreaks ofAntibiotics (Basel, Switzerland) · 2026
    Article
  3. An update on clinically relevant, rare, and emergingClinical microbiology reviews · 2025
    Review
  4. Article
  5. Article
  6. Infection and drug resistance · 2023
    Review
  7. Article
  8. Journal of fungi (Basel, Switzerland) · 2020
    Article
  9. Article
  10. Biofilm Formed byJournal of fungi (Basel, Switzerland) · 2020
    Article
  11. Identification of Cryptic Species of FourJournal of fungi (Basel, Switzerland) · 2019
    Article
  12. On the Origins of a Species: What Might Explain the Rise ofJournal of fungi (Basel, Switzerland) · 2019
    Article
  13. An Update on the Roles of Non-Journal of fungi (Basel, Switzerland) · 2018
    Review
  14. Article
  15. Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Humberto Fabio BoattoUniversidade Federal de São Paulo, Universidade Federal de São Paulo, Departamento de Ginecologia, São Paulo SP , Brasil, Universidade Federal de São Paulo, Departamento de Ginecologia, São Paulo, SP, Brasil.
Sarah Desirée Barbosa CavalcantiUniversidade de São Paulo, Universidade de São Paulo, Hospital das Clínicas da Faculdade de Medicina, São Paulo SP , Brasil, Universidade de São Paulo, Hospital das Clínicas da Faculdade de Medicina, São Paulo, SP, Brasil.
Gilda Mb Del NegroUniversidade de São Paulo, Universidade de São Paulo, Hospital das Clínicas da Faculdade de Medicina, São Paulo SP , Brasil, Universidade de São Paulo, Hospital das Clínicas da Faculdade de Medicina, São Paulo, SP, Brasil.
Manoel João Bc GirãoUniversidade Federal de São Paulo, Universidade Federal de São Paulo, Departamento de Ginecologia, São Paulo SP , Brasil, Universidade Federal de São Paulo, Departamento de Ginecologia, São Paulo, SP, Brasil.
Elaine Cristina FranciscoUniversidade Federal de São Paulo, Universidade Federal de São Paulo, Departamento de Infectologia, São Paulo SP , Brasil, Universidade Federal de São Paulo, Departamento de Infectologia, São Paulo, SP, Brasil.
Kelly IshidaUniversidade de São Paulo, Universidade de São Paulo, Instituto de Ciências Biomédicas, Departamento de Microbiologia, São Paulo SP , Brasil, Universidade de São Paulo, Instituto de Ciências Biomédicas, Departamento de Microbiologia, São Paulo, SP, Brasil.
Olga Fischman GompertzUniversidade Federal de São Paulo, Universidade Federal de São Paulo, Departamento de Microbiologia, Imunologia e Parasitologia, São Paulo SP , Brasil, Universidade Federal de São Paulo, Departamento de Microbiologia, Imunologia e Parasitologia, São Paulo, SP, Brasil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of this study was to identify Candida species isolated from women diagnosed with recurrent vulvovaginal candidiasis (RVVC) and their partners; and to evaluate the fluconazole (FLZ) susceptibility of the isolates. In a period of six years, among 172 patients diagnosed with vulvovaginal candidiasis, 13 women that presented RVVC and their partners were selected for this investigation. The isolates were obtained using Chromagar Candida medium, the species identification was performed by phenotypic and molecular methods and FLZ susceptibility was evaluated by E-test. Among 26 strains we identified 14 Candida albicans, six Candida duobushaemulonii, four Candida glabrata, and two Candida tropicalis. Agreement of the isolated species occurred in 100% of the couples. FLZ low susceptibility was observed for all isolates of C. duobushaemulonii (minimal inhibitory concentration values from 8-> 64 µg/mL), two C. glabrata isolates were FLZ-resistant and all C. albicans and C. tropicalis isolates were FLZ-susceptible. This report emphasises the importance of accurate identification of the fungal agents by a reliable molecular technique in RVVC episodes besides the lower antifungal susceptibility profile of this rare pathogen C. duobushaemulonii to FLZ.

Indexed as

Drug Resistance, FungalAntifungal AgentsBrazilCandidaCandidiasis, VulvovaginalFemaleFluconazoleHumansMaleMicrobial Sensitivity TestsMycological Typing TechniquesRecurrenceAntifungal AgentsFluconazole

Identifiers

PMID27304096
PMCPMC4909041

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.