Evidence map›Paper›PMID 27303570›Full record

ArticleThe Pan African medical journal2016

[Factors associated with the failure of Intermittent Preventive Treatment for malaria among pregnant women in Yaounde].

Félix Essiben, Pascal Foumane, Marcelle Aurelie Tsafack de Nguefack, Filbert Eko Eko, Philip Nana Njotang, Robinson Mbu Enow, Emile Telesphore Mboudou

Open access · greenAbstract readMulticenter Study
PubMed Full text at PMC Publisher
In one paragraph

Article in The Pan African medical journal, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

Félix EssibenDépartement de Gynécologie-Obstétrique, Faculté de Médecine et des Sciences Biomédicales de l'Université de Yaoundé, Cameroun; Hôpital Central de Yaoundé (HCY), Cameroun.
Pascal FoumaneDépartement de Gynécologie-Obstétrique, Faculté de Médecine et des Sciences Biomédicales de l'Université de Yaoundé, Cameroun; Hôpital Gynéco-obstétrique et Pédiatrique de Yaoundé, Cameroun.
Marcelle Aurelie Tsafack de NguefackInstitut de Technologie Médicale de Yaoundé
Filbert Eko EkoHôpital Central de Yaoundé (HCY), Cameroun; Institut de Technologie Médicale de Yaoundé
Philip Nana NjotangDépartement de Gynécologie-Obstétrique, Faculté de Médecine et des Sciences Biomédicales de l'Université de Yaoundé, Cameroun; Hôpital Central de Yaoundé (HCY), Cameroun.
Robinson Mbu EnowDépartement de Gynécologie-Obstétrique, Faculté de Médecine et des Sciences Biomédicales de l'Université de Yaoundé, Cameroun; Hôpital Central de Yaoundé (HCY), Cameroun.
Emile Telesphore MboudouDépartement de Gynécologie-Obstétrique, Faculté de Médecine et des Sciences Biomédicales de l'Université de Yaoundé, Cameroun; Hôpital Gynéco-Obstétrique et Pédiatrique de Douala, Cameroun.
Université de Yaoundé I · CMYaoundé Gynaecology, Obstetrics and Pediatrics Hospital · CMCentral Hospital of Yaoundé · CMTechnologie Médicale (France) · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionIntermittent preventive treatment with sulfadoxine-pyrimethamine (IPTp-SP) is recommended for malaria prevention during pregnancy. We investigated factors associated with the failure of this strategy.

methodsWe conducted a case-control study in two health care facilities in Yaounde, from 1 May 2014 to 30 April 2015. Pregnant women treated with IPTp-SP, hospitalized for malaria and having a positive Rapid Diagnostic Test (RDT) result (case-subjects) were compared to pregnant women treated with IPTp-SP having a negative RDT result (control-subjects). Epi Info 7 software and SPSS 18.0 software were used with P< 0.05 as significance threshold.

resultsWe recruited 234 subjects, 109 (46.6%) case-subjects and 125 control-subjects (53.4%). The associated factors found were: prematurity (P=0.03; OR=1.15; IC= 0.32 - 4.10), the non-use of LLIN (P=0.006; OR= 2.31; IC= 1.26 - 4.25), a history of hospitalization for malaria (P=0.007; OR= 2.19; IC= 1.23 - 3.89), IPTp-SP administration after 28 gestational weeks (P=0.001, OR= 3.55; IC= 1.7 - 7.61). After logistic regression, prematurity (P=0.024; OR=2.01; IC=1.1-3.7) and a history of hospitalization for malaria (P=0.001; OR=2.83; IC=1.50-5.4) remained associated with IPTp-SP failure.

conclusionA history of hospitalization for malaria and prematurity are independent predictor of IPTp-SP failure.

Indexed as

AdultAntimalarialsCameroonCase-Control StudiesDrug CombinationsFemaleHospitalizationHumansLogistic ModelsMalariaPregnancyPregnancy Complications, ParasiticPyrimethamineRisk FactorsSulfadoxineTreatment FailureAntimalarialsDrug Combinationsfanasil, pyrimethamine drug combinationPyrimethamineSulfadoxineCameroonintermittent preventive treatmentmalariaRisk factorssulphadoxine-pyrimethamine

Identifiers

PMID27303570
PMCPMC4894739
OpenAlexW2319405560

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.