Evidence map›Paper›PMID 27303306›Full record

ReviewFrontiers in physiology2016

Electrophysiological Mechanisms of Bayés Syndrome: Insights from Clinical and Mouse Studies.

Gary Tse, Eric Tsz Him Lai, Jie Ming Yeo, Bryan P Yan

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in physiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
8.1field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 43 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Atrial Conduction Disorders.Current cardiology reviews · 2021
    Review
  5. Article
  6. Frontiers in bioengineering and biotechnology · 2020
    Article
  7. Article
  8. New electrocardiographic score for the prediction of atrial fibrillation: The MVP ECG risk score (morphology-voltage-P-wave duration).Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc · 2019
    Article
  9. Article
  10. A rare case ofJournal of geriatric cardiology : JGC · 2019
    Article
  11. Review
  12. Article
  13. Novel arrhythmic risk markers incorporating QRS dispersion: QRSAnnals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc · 2017
    Article
  14. Determination of action potential wavelength restitution inJournal of geriatric cardiology : JGC · 2017
    Article
  15. Bayés syndrome and acute cardioembolic ischemic stroke.World journal of clinical cases · 2017
    Review
  16. Electrophysiological mechanisms of long and short QT syndromes.International journal of cardiology. Heart & vasculature · 2017
    Review
  17. The role of gap junctions in inflammatory and neoplastic disorders (Review).International journal of molecular medicine · 2017
    Review
  18. Review
  19. Animal models of atherosclerosis.Biomedical reports · 2017
    Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 4 countries.

Gary TseLi Ka Shing Faculty of Medicine, School of Biomedical Sciences, University of Hong Kong Hong Kong, China.
Eric Tsz Him LaiLi Ka Shing Faculty of Medicine, School of Biomedical Sciences, University of Hong Kong Hong Kong, China.
Jie Ming YeoSchool of Medicine, Imperial College London London, UK.
Bryan P YanDepartment of Medicine and Therapeutics, The Chinese University of Hong KongHong Kong, China; Department of Epidemiology and Preventive Medicine, Monash UniversityMelbourne, VIC, Australia.
Chinese University of Hong Kong · CNImperial College London · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bayés syndrome is an under-recognized clinical condition characterized by inter-atrial block (IAB). This is defined electrocardiographically as P-wave duration > 120 ms and can be categorized into first, second and third degree IAB. It can be caused by inflammatory conditions such as systemic sclerosis and rheumatoid arthritis, abnormal protein deposition in cardiac amyloidosis, or neoplastic processes invading the inter-atrial conduction system, such as primary cardiac lymphoma. It may arise transiently during volume overload, autonomic dysfunction or electrolyte disturbances from vomiting. In other patients without an obvious cause, the predisposing factors are diabetes mellitus, hypertensive heart disease, and hypercholesterolemia. IAB has a strong association with atrial arrhythmogenesis, left atrial enlargement (LAE), and electro-mechanical discordance, increasing the risk of cerebrovascular accidents as well as myocardial and mesenteric ischemia. The aim of this review article is to synthesize experimental evidence on the pathogenesis of IAB and its underlying molecular mechanisms. Current medical therapies include anti-fibrotic, anti-arrhythmic and anti-coagulation agents, whereas interventional options include atrial resynchronization therapy by single or multisite pacing. Future studies will be needed to elucidate the significance of the link between IAB and atrial tachyarrhythmias in patients with different underlying etiologies and optimize the management options in these populations.

Indexed as

Bayés syndromeconductionelectrophysiological remodelinginter-atrial blockintra-atrial blockstructural remodeling

Identifiers

PMID27303306
PMCPMC4886053
OpenAlexW2417084441

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.