ArticleProceedings of the National Academy of Sciences of the United States of America2016
Metabolomics of aging requires large-scale longitudinal studies with replication.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed.
- Metabolite signatures of chronological age, aging, survival, and longevity.Cell reports · 2024Article
- Towards Healthy Longevity: Comprehensive Insights from Molecular Targets and Biomarkers to Biological Clocks.International journal of molecular sciences · 2024Review
- Influence of age and sex on longitudinal metabolic profiles and body weight trajectories in the UK Biobank.International journal of epidemiology · 2024Article
- Accurate detection of acute sleep deprivation using a metabolomic biomarker-A machine learning approach.Science advances · 2024Article
- Past or Present; Which Exposures Predict Metabolomic Aging Better? The Doetinchem Cohort Study.The journals of gerontology. Series A, Biological sciences and medical sciences · 2024Article
- Cross-sectionally Calculated Metabolic Aging Does Not Relate to Longitudinal Metabolic Changes-Support for Stratified Aging Models.The Journal of clinical endocrinology and metabolism · 2023Article
- Longitudinal metabolomics of increasing body-mass index and waist-hip ratio reveals two dynamic patterns of obesity pandemic.International journal of obesity (2005) · 2023Observational
- The metabolomics of human aging: Advances, challenges, and opportunities.Science advances · 2022Review
- Cutaneous Thermal Injury Modulates Blood and Skin Metabolomes Differently in a Murine Model.Journal of burn care & research : official publication of the American Burn Association · 2021Article
- Review
- Ageing Investigation Using Two-Time-Point Metabolomics Data from KORA and CARLA Studies.Metabolites · 2019Article
- Article
- Beyond genomics: understanding exposotypes through metabolomics.Human genomics · 2018Review
- A procession of metabolic alterations accompanying muscle senescence in Manduca sexta.Scientific reports · 2018Article
- Proteomics and metabolomics in ageing research: from biomarkers to systems biology.Essays in biochemistry · 2017Review
- Reply to Mäkinen and Ala-Korpela: Small-scale but accurate metabolomics with high reproducibility for identifying age-related blood metabolites.Proceedings of the National Academy of Sciences of the United States of America · 2016Article
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.