ReviewDevelopment (Cambridge, England)2016
Extracellular matrix motion and early morphogenesis.
Review in Development (Cambridge, England), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
41 citing papers in PubMed.
- Supracellular Mechanics and Counter-Rotational Bilateral Flows Orchestrate Posterior Morphogenesis.bioRxiv : the preprint server for biology · 2025Article
- Transcriptomic analysis in peripheral blood mononuclear cells from hyper and hypo weight-loss responders.Genes & nutrition · 2025Article
- Article
- An eGFP-Col4a2 mouse model reveals basement membrane dynamics underlying hair follicle morphogenesis.The Journal of cell biology · 2025Article
- Mobilization of subcutaneous fascia contributes to the vascularization and function of acellular adipose matrix via formation of vascular matrix complex.Materials today. Bio · 2025Article
- Live Cell Imaging of Bone Cell and Organ Cultures.Methods in molecular biology (Clifton, N.J.) · 2025Article
- Article
- Sex-Specific Transcriptomic Changes in the Villous Tissue of Placentas of Pregnant Women Using a Selective Serotonin Reuptake Inhibitor.ACS chemical neuroscience · 2024Article
- Organogenetic transcriptomes of the Drosophila embryo at single cell resolution.Development (Cambridge, England) · 2024Article
- Article
- In vivo fluorescent labeling and tracking of extracellular matrix.Nature protocols · 2023Review
- Microenvironment-targeted strategy steers advanced bone regeneration.Materials today. Bio · 2023Review
- Extracellular matrix remodelling in obesity and metabolic disorders.Life metabolism · 2023Article
- Extracellular matrix assembly stress initiates Drosophila central nervous system morphogenesis.Developmental cell · 2023Article
- Cell Response in Free-Packed Granular Systems.ACS applied materials & interfaces · 2022Article
- Static and Dynamic Biomaterial Engineering for Cell Modulation.Nanomaterials (Basel, Switzerland) · 2022Review
- Modeling human neurodevelopmental diseases with brain organoids.Cell regeneration (London, England) · 2022Review
- The ECM: To Scaffold, or Not to Scaffold, That Is the Question.International journal of molecular sciences · 2021Review
- Actuation enhances patterning in human neural tube organoids.Nature communications · 2021Article
- Microengineered 3D Collagen Gels with Independently Tunable Fiber Anisotropy and Directionality.Advanced materials technologies · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
Abstract
For over a century, embryologists who studied cellular motion in early amniotes generally assumed that morphogenetic movement reflected migration relative to a static extracellular matrix (ECM) scaffold. However, as we discuss in this Review, recent investigations reveal that the ECM is also moving during morphogenesis. Time-lapse studies show how convective tissue displacement patterns, as visualized by ECM markers, contribute to morphogenesis and organogenesis. Computational image analysis distinguishes between cell-autonomous (active) displacements and convection caused by large-scale (composite) tissue movements. Modern quantification of large-scale 'total' cellular motion and the accompanying ECM motion in the embryo demonstrates that a dynamic ECM is required for generation of the emergent motion patterns that drive amniote morphogenesis.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.