SIRT7 clears the way for DNA repair.

Silvana Paredes, Katrin F Chua

Abstract readComment

In one paragraph

Article in The EMBO journal, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it

0cells of the map it votes in

8citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

YZL-51N functions as a selective inhibitor of SIRT7 by NADiScience · 2024
Article
In situ observation of mitochondrial biogenesis as the early event of apoptosis.iScience · 2021
Article
Patrolling human SLE haematopoietic progenitors demonstrate enhanced extramedullary colonisation; implications for peripheral tissue injury.Scientific reports · 2021
Article
HIV-1 Vpr activates host CRL4-DCAF1 E3 ligase to degrade histone deacetylase SIRT7.Virology journal · 2021
Article
Role of sirtuins in bone biology: Potential implications for novel therapeutic strategies for osteoporosis.Aging cell · 2021
Review
SIRT6 is a DNA double-strand break sensor.eLife · 2020
Article
A role of the 53BP1 protein in genome protection: structural and functional characteristics of 53BP1-dependent DNA repair.Aging · 2019
Review
A Click Chemistry Approach Reveals the Chromatin-Dependent Histone H3K36 Deacylase Nature of SIRT7.Journal of the American Chemical Society · 2019
Article

4 · The record

Corrections and comments

Comment on
SIRT7 promotes genome integrity and modulates non-homologous end joining DNA repair.2016

5 · Who and what money

Authors and funding

2 authors.

Silvana ParedesDepartment of Medicine, Stanford University School of Medicine, Stanford, CA, USA Geriatric Research, Education, and Clinical Center, Veterans Affairs Palo Alto Health Care System, Palo Alto, CA, USA.

Katrin F ChuaDepartment of Medicine, Stanford University School of Medicine, Stanford, CA, USA Geriatric Research, Education, and Clinical Center, Veterans Affairs Palo Alto Health Care System, Palo Alto, CA, USA.

Funding

Elucidating functions of mammalian SIRT7 deacetylase in aging and diseaseI01BX000286 · VA · VETERANS ADMIN PALO ALTO HEALTH CARE SYS · PI Katrin F. Chua · 2009 to 2026

–

BLRD VA I01 BX000286

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

DNA RepairHumansSirtuinsSirtuins

Identifiers

PMID27302089

DOI10.15252/embj.201694904

PMCPMC4946144

What OpenQuestion holds

Textmetadata

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.