ReviewStroke2016
Vascular Contributions to Cognitive Impairment and Dementia: Topical Review of Animal Models.
Abstract readReview
In one paragraph
Review in Stroke, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 1 of them a synthesis that pooled it.
0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed, 1 pooled it
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
35 citing papers in PubMed, 1 synthesis or guideline pooled it.
- UK consensus on pre-clinical vascular cognitive impairment functional outcomes assessment: Questionnaire and workshop proceedings.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2020Pooled it
- Spatially and temporally progressive hypoperfusion in Alzheimer's disease revealed by normative modeling.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026Article
- From artery to memory: a comparative review of vascular cognitive impairment surgical models.Frontiers in aging neuroscience · 2026Review
- A Minimally Invasive Framework Reveals Region-Specific Cerebrovascular Remodeling in Aging Using Intravital Functional Ultrasound Imaging and Ultrasound Localization Microscopy (fUS-ULM).Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Cerebrovascular p16Acta neuropathologica communications · 2025Article
- Interplay Between Vascular Dysfunction and Neurodegenerative Pathology: New Insights into Molecular Mechanisms and Management.Biomolecules · 2025Review
- Combination treatment with cilostazol and isosorbide mononitrate attenuates microemboli-mediated vascular cognitive impairment and improves imaging and plasma biomarkers in diabetic rats.Experimental neurology · 2025Article
- PNA5, A Novel Mas Receptor Agonist, Improves Neurovascular and Blood-Brain-Barrier Function in a Mouse Model of Vascular Cognitive Impairment and Dementia.Aging and disease · 2024Article
- Cerebrovascular reactivity MRI as a biomarker for cerebral small vessel disease-related cognitive decline: Multi-site validation in the MarkVCID Consortium.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2024Article
- Progressive Disruption of Sphingosine-1-Phosphate Receptor 1 Correlates with Blood-Brain Barrier Leakage in A Rat Model of Chronic Hypoxic Hypoperfusion.Aging and disease · 2024Article
- Targeting Astrocyte Signaling Alleviates Cerebrovascular and Synaptic Function Deficits in a Diet-Based Mouse Model of Small Cerebral Vessel Disease.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2023Article
- Natural Bioactive Molecules as Neuromedicines for the Treatment/Prevention of Neurodegenerative Diseases.ACS omega · 2023Review
- A multi-disciplinary commentary on preclinical research to investigate vascular contributions to dementia.Cerebral circulation - cognition and behavior · 2023Review
- Deeper cerebral hypoperfusion leads to spatial cognitive impairment in mice.Stroke and vascular neurology · 2022Article
- Vascular cognitive impairment and dementia: An early career researcher perspective.Alzheimer's & dementia (Amsterdam, Netherlands) · 2022Article
- A functional cerebral endothelium is necessary to protect against cognitive decline.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2022Article
- Characterizing the Neuroimaging and Histopathological Correlates of Cerebral Small Vessel Disease in Spontaneously Hypertensive Stroke-Prone Rats.Frontiers in neurology · 2021Article
- Cognitive Sequelae of Silent Ischemic Lesions Following Carotid Artery Stenting: Possible Role of Age-Related Moderation.Frontiers in aging neuroscience · 2021Article
- Diabetic rats are more susceptible to cognitive decline in a model of microemboli-mediated vascular contributions to cognitive impairment and dementia.Brain research · 2020Article
- Exploring the Potential of Mesenchymal Stem Cell-Based Therapy in Mouse Models of Vascular Cognitive Impairment.International journal of molecular sciences · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Jeremy B MadiganFrom the Cardiovascular and Cell Sciences Research Institute, St George's University of London, London, United Kingdom (J.B.M., A.H.H.); Neuroradiology Department, St George's Hospital, London, United Kingdom (J.B.M.); Atkinson Morley Neurosciences, St George's University Hospitals NHS Foundation Trust, London, United Kingdom (J.B.M., A.H.H.); and Sanders-Brown Center on Aging, University of Kentucky, Lexington (D.M.W.).
Donna M WilcockFrom the Cardiovascular and Cell Sciences Research Institute, St George's University of London, London, United Kingdom (J.B.M., A.H.H.); Neuroradiology Department, St George's Hospital, London, United Kingdom (J.B.M.); Atkinson Morley Neurosciences, St George's University Hospitals NHS Foundation Trust, London, United Kingdom (J.B.M., A.H.H.); and Sanders-Brown Center on Aging, University of Kentucky, Lexington (D.M.W.).
Atticus H HainsworthFrom the Cardiovascular and Cell Sciences Research Institute, St George's University of London, London, United Kingdom (J.B.M., A.H.H.); Neuroradiology Department, St George's Hospital, London, United Kingdom (J.B.M.); Atkinson Morley Neurosciences, St George's University Hospitals NHS Foundation Trust, London, United Kingdom (J.B.M., A.H.H.); and Sanders-Brown Center on Aging, University of Kentucky, Lexington (D.M.W.). ahainsworth@sgul.ac.uk.
Funding
Vascular breakdown in Alzheimers Disease with cerebrovascular diseaseR01NS079637 · NINDS · UNIVERSITY OF KENTUCKY · PI WILCOCK, DONNA M · 2012 to 2016
$1.6MAlzheimer's Society 151National Centre for the Replacement, Refinement and Reduction of Animals in Research G0800701/1NINDS NIH HHS R01 NS079637
Abstract
PubMed holds no abstract for this paper.
Indexed as
Cerebrovascular CirculationModels, AnimalAnimalsCognition DisordersCognitive DysfunctionDementiaDisease Models, AnimalHumansMicePapioRatsAlzheimer diseasecerebral small vessel diseasecerebrovascular circulationhyperhomocysteinemiavascular dementia
Identifiers
What OpenQuestion holds
Textmetadata
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Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.