Evidence map›Paper›PMID 27301661›Full record

ArticleThe Journal of antibiotics2016

Methyltransferases excised from trans-AT polyketide synthases operate on N-acetylcysteamine-bound substrates.

D Cole Stevens, Drew T Wagner, Hannah R Manion, Bradley K Alexander, Adrian T Keatinge-Clay

Abstract read
In one paragraph

Article in The Journal of antibiotics, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Fatuamide A, a Hybrid PKS/NRPS Metallophore from aJournal of natural products · 2025
    Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Review
  7. Chemistry of a Unique Polyketide-like Synthase.Journal of the American Chemical Society · 2018
    Article
  8. Review
  9. Article
  10. Polyketide stereocontrol: a study in chemical biology.Beilstein journal of organic chemistry · 2017
    Review
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

D Cole Stevens *Department of Molecular Biosciences, The University of Texas at Austin, Austin, Texas, USA.
Drew T Wagner *Department of Molecular Biosciences, The University of Texas at Austin, Austin, Texas, USA.
Hannah R ManionDepartment of Molecular Biosciences, The University of Texas at Austin, Austin, Texas, USA.
Bradley K AlexanderDepartment of Molecular Biosciences, The University of Texas at Austin, Austin, Texas, USA.
Adrian T Keatinge-ClayDepartment of Molecular Biosciences, The University of Texas at Austin, Austin, Texas, USA.

Funding

Determining the Architectures and Activities of Polyketide Synthase ModulesR01GM106112 · NIGMS · UNIVERSITY OF TEXAS AT AUSTIN · PI KEATINGE-CLAY, ADRIAN TRISTAN · 2013 to 2025
$3.9M
NIGMS NIH HHS R01 GM106112
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Bacillus amyloliquefaciensCloning, MolecularCysteamineEscherichia coliGene ExpressionKineticsMethyltransferasesPolyketide SynthasesPseudomonas fluorescensRecombinant ProteinsSubstrate SpecificityCysteamineMethyltransferasesPolyketide SynthasesRecombinant Proteins

Identifiers

PMID27301661
PMCPMC4963292

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.