ArticleNeuropsychologia2016
Dissociation of quantifiers and object nouns in speech in focal neurodegenerative disease.
Article in Neuropsychologia, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.
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Who cites it
11 citing papers in PubMed, 1 synthesis or guideline pooled it, 27 citations in OpenAlex.
- Speech and language impairments in behavioral variant frontotemporal dementia: A systematic review.Neuroscience and biobehavioral reviews · 2021Pooled it
- Quantifier processing and semantic flexibility in patients with aphasia.Frontiers in psychology · 2024Article
- Cognitive and social well-being in older adulthood: The CoSoWELL corpus of written life stories.Behavior research methods · 2023Article
- Concrete and Abstract Concepts in Primary Progressive Aphasia and Alzheimer's Disease: A Scoping Review.Brain sciences · 2023Article
- A syntax-lexicon trade-off in language production.Proceedings of the National Academy of Sciences of the United States of America · 2022Article
- Automated analysis of lexical features in frontotemporal degeneration.Cortex; a journal devoted to the study of the nervous system and behavior · 2021Article
- Automated analysis of lexical features in Frontotemporal Degeneration.medRxiv : the preprint server for health sciences · 2020Article
- Primary Progressive Aphasia and Stroke Aphasia.Continuum (Minneapolis, Minn.) · 2018Review
- Linguistic Aspects of Primary Progressive Aphasia.Annual review of linguistics · 2018Article
- Decision-Making Deficits Associated with Amyloidosis in Lewy Body Disorders.Frontiers in human neuroscience · 2016Article
- Language in corticobasal syndrome: a systematic review.Dementia & neuropsychologiaArticle
Corrections and comments
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Authors and funding
9 authors at 1 institution in 1 country.
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Abstract
Quantifiers such as many and some are thought to depend in part on the conceptual representation of number knowledge, while object nouns such as cookie and boy appear to depend in part on visual feature knowledge associated with object concepts. Further, number knowledge is associated with a frontal-parietal network while object knowledge is related in part to anterior and ventral portions of the temporal lobe. We examined the cognitive and anatomic basis for the spontaneous speech production of quantifiers and object nouns in non-aphasic patients with focal neurodegenerative disease associated with corticobasal syndrome (CBS, n=33), behavioral variant frontotemporal degeneration (bvFTD, n=54), and semantic variant primary progressive aphasia (svPPA, n=19). We recorded a semi-structured speech sample elicited from patients and healthy seniors (n=27) during description of the Cookie Theft scene. We observed a dissociation: CBS and bvFTD were significantly impaired in the production of quantifiers but not object nouns, while svPPA were significantly impaired in the production of object nouns but not quantifiers. MRI analysis revealed that quantifier production deficits in CBS and bvFTD were associated with disease in a frontal-parietal network important for number knowledge, while impaired production of object nouns in all patient groups was related to disease in inferior temporal regions important for representations of visual feature knowledge of objects. These findings imply that partially dissociable representations in semantic memory may underlie different segments of the lexicon.
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