Evidence map›Paper›PMID 27301295›Full record

ArticleBMC public health2016

Association of adiponectin and socioeconomic status in African American men and women: the Jackson heart study.

Sharon K Davis, Ruihua Xu, Pia Riestra, Samson Y Gebreab, Rumana J Khan, Amadou Gaye, DeMarc Hickson, Mario Sims, Aurelian Bidulescu

Open access · goldAbstract read
In one paragraph

Article in BMC public health, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.5field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Sharon K DavisSocial Epidemiology Research Unit, National Human Genome Research Institute, National Institutes of Health, 10 Center Drive, Room 7 N320, MSC 1644, Bethesda, 20892, MD, USA. sharon.davis@nih.gov.
Ruihua XuSocial Epidemiology Research Unit, National Human Genome Research Institute, National Institutes of Health, 10 Center Drive, Room 7 N320, MSC 1644, Bethesda, 20892, MD, USA.
Pia RiestraSocial Epidemiology Research Unit, National Human Genome Research Institute, National Institutes of Health, 10 Center Drive, Room 7 N320, MSC 1644, Bethesda, 20892, MD, USA.
Samson Y GebreabSocial Epidemiology Research Unit, National Human Genome Research Institute, National Institutes of Health, 10 Center Drive, Room 7 N320, MSC 1644, Bethesda, 20892, MD, USA.
Rumana J KhanSocial Epidemiology Research Unit, National Human Genome Research Institute, National Institutes of Health, 10 Center Drive, Room 7 N320, MSC 1644, Bethesda, 20892, MD, USA.
Amadou GayeSocial Epidemiology Research Unit, National Human Genome Research Institute, National Institutes of Health, 10 Center Drive, Room 7 N320, MSC 1644, Bethesda, 20892, MD, USA.
DeMarc HicksonUniversity of Mississippi Medical Center, Jackson, USA.
Mario SimsUniversity of Mississippi Medical Center, Jackson, USA.
Aurelian BidulescuUniversity of Indiana, School of Public Health, Bloomington, USA.
National Institutes of Health · USIndiana University Bloomington · USJackson Memorial Hospital · USUniversity of Mississippi Medical Center · US

Funding

CTSA INFRASTRUCTURE FOR PEDIATRIC RESEARCHUL1RR025008 · NCRR · EMORY UNIVERSITY · PI STEPHENS, DAVID S · 2007 to 2011
$29.0M
Atlanta Clinical and Translational Science Institute (ACTSI) RenewalUL1TR000454 · NCATS · EMORY UNIVERSITY · PI STEPHENS, DAVID S · 2012 to 2016
$25.8M
Cardiovascular Disease Preventive Intervention ProgramUH1HL073461 · NHLBI · MOREHOUSE SCHOOL OF MEDICINE · PI DAVIS, SHARON K · 2003 to 2010
$3.7M
NCATS NIH HHS UL1 TR000454NCRR NIH HHS UL1 RR025008NHLBI NIH HHS HHSN268201300050CNHLBI NIH HHS UH1 HL073461
6 · The paper itself

Abstract

backgroundRecent emphasis has been placed on elucidating the biologic mechanism linking socioeconomic status (SES) to cardiovascular disease (CVD). Positive associations of inflammatory biomarkers provide evidence suggestive of a biologic pathway by which SES may predispose to CVD. African Americans have disproportionately lower SES and have a higher prevalence of CVD risk factors compared to most ethnic/racial groups. Adiponectin (an anti-inflammatory marker) is also lower. The objective of this study was to assess the association of adiponectin with SES among African American men and women using the Jackson Heart Study.

methodsStudy sample included 4340 participants. Linear regression was performed separately by SES and stratified by sex. Annual household income and level of education was used as proxies for SES. Crude, age, health behavior and health status adjusted models were analyzed. The main outcome was log-transformed adiponectin.

resultsMen in the lowest income group had significantly higher adiponectin than those in the highest income group in the fully adjusted model (ß/standard error [se], p value = .16/.08, p = .0008. Men with < high school level of education had significantly higher adiponectin in the crude and age adjusted models than those with ≥ college degree (.25/.05, p < .0001; .14/.05/ p = .005, respectively). Women with some college or vocational training in the crude and age adjusted models had lower adiponectin compared to women with ≥ college degree (-.09/.03, p = .004; -.06/.03, p = .04, respectively).

conclusionFindings suggest a potential inverse biologic pathway between annual household income and adiponectin among African American men. There was no such finding among women. Findings suggest interventions should be targeted for higher SES African American men to improve adiponectin levels.

Indexed as

Social ClassAdiponectinAdultAgedAged, 80 and overBiomarkersBlack or African AmericanCardiovascular DiseasesCross-Sectional StudiesFemaleHumansIncomeLinear ModelsMaleMiddle AgedMississippiAdiponectinBiomarkersAdiponectinAfrican AmericansBiomarkersCardiovascular diseaseSocioeconomic status

Identifiers

PMID27301295
PMCPMC4908712
OpenAlexW2441000139

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.