Evidence map›Paper›PMID 27300498›Full record

Trial reportJournal of neuroimaging : official journal of the American Society of Neuroimaging2017

Utilization of Emergent Neuroimaging for Thrombolysis-Eligible Stroke Patients.

Nerses Sanossian, Katherine A Fu, David S Liebeskind, Sidney Starkman, Scott Hamilton, J Pablo Villablanca, Adrian M Burgos, Robin Conwit, Jeffrey L Saver

Open access · greenAbstract readClinical Trial, Phase IIIRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Journal of neuroimaging : official journal of the American Society of Neuroimaging, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 28 citations in OpenAlex.

  1. Article
  2. Review
  3. Observational
  4. Large vessel occlusion detection by non-contrast CT using artificial ıntelligence.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2024
    Article
  5. A Case-Control Study of Distinguishing Between Stroke Mimics and True Strokes.Journal of community hospital internal medicine perspectives · 2022
    Article
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Nerses SanossianRoxanna Todd Hodges Comprehensive Stroke Clinic and Department of Neurology, University of Southern California, Los Angeles, CA.
Katherine A FuRoxanna Todd Hodges Comprehensive Stroke Clinic and Department of Neurology, University of Southern California, Los Angeles, CA.
David S LiebeskindNeurovascular Imaging Research Core, Los Angeles, CA.
Sidney StarkmanStroke Center, University of California Los Angeles, Los Angeles, CA.
Scott HamiltonStanford University, Stanford, CA.
J Pablo VillablancaStroke Center, University of California Los Angeles, Los Angeles, CA.
Adrian M BurgosRoxanna Todd Hodges Comprehensive Stroke Clinic and Department of Neurology, University of Southern California, Los Angeles, CA.
Robin ConwitNational Institute of Neurological Disorders and Stroke, Bethesda, MD.
Jeffrey L SaverStroke Center, University of California Los Angeles, Los Angeles, CA.
University of California, Los Angeles · USUniversity of Southern California · USNational Institute of Neurological Disorders and Stroke · USStanford University · US

Funding

Field Administration of Stroke Therapy-Magnesium Trial (FAST-MAG)U01NS044364 · NINDS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI SAVER, JEFFREY L · 2003 to 2013
$46.4M
NINDS NIH HHS U01 NS044364
6 · The paper itself

Abstract

backgroundAdvances in diagnostic imaging of stroke include multimodal techniques such as noninvasive angiography and perfusion imaging. We aimed to characterize trends in neuroimaging utilization among acute stroke patients. Utilization of multimodal imaging for acute stroke in the community has remained largely uncharacterized despite its increased adoption at academic medical centers.

methodsWe quantified neuroimaging utilization in the emergency department (ED) for 1,700 hyperacute stroke patients presenting <2 hours after symptom onset who participated in the National Institutes of Health Field Administration of Stroke Therapy-Magnesium (FAST-MAG) study throughout Los Angeles and Orange Counties. FAST-MAG provided no recommendation as to imaging utilization.

resultsA total of 1,700 cases were imaged a median (interquartile range [IQR]) of 92 (74-120) minutes after last known well time and 28 (19-41) minutes after ED arrival. The initial scanner used in the ED was computed tomography (CT) in a preponderance of cases (N = 1,612, 95%), with magnetic resonance imaging (MRI) in 88 cases (5%). CT angiography (CTA) was obtained in 192 (11%) and perfusion CT (CTP) in 91 (5.4%) cases. MRI imaging was universally obtained using diffusion-weighted images, 60% with MR angiography and 33% included perfusion imaging. Rates of concomitant CTA or CTP use increased in the later years of the study from 4% in 2005-2006, 2% in 2007-2008, 8% in 2009-2010, and 26% in 2011-2012 (P for trend < .001).

conclusionsAmong acute stroke patients, noncontrast CT was the most common initial imaging strategy in clinical practice in the 2005-2012 time period, though use of concomitant CTA grew to one-quarter of cases, suggestive of an upward trend.

Indexed as

Thrombolytic TherapyAgedAged, 80 and overCaliforniaCerebral AngiographyComputed Tomography AngiographyDiffusion Magnetic Resonance ImagingEmergenciesEmergency Service, HospitalFemaleHumansMagnetic Resonance AngiographyMaleMiddle AgedMultimodal ImagingNeuroimagingemergency medical servicesImagingprehospitalstroke

Identifiers

PMID27300498
PMCPMC5156583
OpenAlexW2437078189

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.