Evidence map›Paper›PMID 27300105›Full record

ArticleeLife2016

A large field of view two-photon mesoscope with subcellular resolution for in vivo imaging.

Nicholas James Sofroniew, Daniel Flickinger, Jonathan King, Karel Svoboda

Abstract read
In one paragraph

Article in eLife, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 388 papers.

0numbers the graph read from it
0cells of the map it votes in
388citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

388 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Towards maximizing optical access through Smart Dura.Journal of neural engineering · 2026
    Article
  5. Article
  6. Mesolens imaging in microbiology.Essays in biochemistry · 2026
    Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Stars2Cells: Astrometric Tracking of Neurons Across Imaging Sessions.bioRxiv : the preprint server for biology · 2026
    Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article

328 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Nicholas James SofroniewJanelia Research Campus, Howard Hughes Medical Institute, Ashburn, United States.
Daniel FlickingerJanelia Research Campus, Howard Hughes Medical Institute, Ashburn, United States.ORCID 0000-0002-8361-3122
Jonathan KingVidrio Technologies, Ashburn, United States.
Karel SvobodaJanelia Research Campus, Howard Hughes Medical Institute, Ashburn, United States.ORCID 0000-0002-6670-7362

Funding

Cellular-resolution multi-region optical recording of neural activity with wide-field two-photon microscopyR43MH110021 · NIMH · VIDRIO TECHNOLOGIES, LLC · PI CLACK, NATHAN G · 2015 to 2015
$225k
Howard Hughes Medical InstituteNIMH NIH HHS R43 MH110021
6 · The paper itself

Abstract

Imaging is used to map activity across populations of neurons. Microscopes with cellular resolution have small (.

Indexed as

AnimalsBrainFemaleIntravital MicroscopyMaleMiceNeuronsOptical Imaging2-photonbarrel cortexbiophysicscalciumdendritic spinesmouseneural codingneurosciencestructural biologytwo-photon

Identifiers

PMID27300105
PMCPMC4951199

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.