Evidence map›Paper›PMID 27300031›Full record

ReviewJournal of endocrinological investigation2016

Fertility in women of late reproductive age: the role of serum anti-Müllerian hormone (AMH) levels in its assessment.

B Meczekalski, A Czyzyk, M Kunicki, A Podfigurna-Stopa, L Plociennik, G Jakiel, M Maciejewska-Jeske, K Lukaszuk

Erratum issuedOpen access · hybridAbstract readReview
In one paragraph

Review in Journal of endocrinological investigation, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 35 papers.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed
10.1field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 85 citations in OpenAlex.

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  14. Mechanisms of ovarian aging in women: a review.Journal of ovarian research · 2023
    Review
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

B MeczekalskiDepartment of Gynecological Endocrinology, Poznan University of Medical Sciences, ul. Polna 33, Poznan, Poland. blazejmeczekalski@yahoo.com.
A CzyzykDepartment of Gynecological Endocrinology, Poznan University of Medical Sciences, ul. Polna 33, Poznan, Poland.
M KunickiINVICTA Fertility and Reproductive Center, Gdańsk, Poland.
A Podfigurna-StopaDepartment of Gynecological Endocrinology, Poznan University of Medical Sciences, ul. Polna 33, Poznan, Poland.
L PlociennikINVICTA Fertility and Reproductive Center, Gdańsk, Poland.
G JakielINVICTA Fertility and Reproductive Center, Warsaw, Poland.
M Maciejewska-JeskeDepartment of Gynecological Endocrinology, Poznan University of Medical Sciences, ul. Polna 33, Poznan, Poland.
K LukaszukINVICTA Fertility and Reproductive Center, Gdańsk, Poland.
Poznan University of Medical Sciences · PLGdańsk Medical University · PLPostgraduate School of Molecular Medicine · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionFertility is referred to the capability for having offspring and can be evaluated by fertility rate. Women's fertility is strictly dependent on individual's age. The fertility peak occurs in the early 20s, and it starts to decline in the third and fourth decades of life (falling sharply after age 35).

aimThe aim of this work is to review the available data concerning fertility in women of late reproductive age, especially the role of serum anti-Müllerian hormone (AMH) levels.

resultsThere are a lot of factors responsible for decrease of fertility in women of late reproductive age. These factors can be classified as oocyte-dependent (decrease in oocyte quantity and quality) and oocyte-independent (reproductive organs [uterus, oviducts] status and general health). Anti-Müllerian hormone (AMH) is a dimeric glycoprotein of the transforming growth factor-β (TGF-β) superfamily produced directly by the ovarian granulosa cells of secondary, preantral, and early antral follicles. It has been used as an ovarian reserve marker since 2002. Anti-Müllerian hormone seems to be the best endocrine marker for assessing the age-related decline of the ovarian pool in healthy women. Evaluation of AMH's predictive value in the naturally aging population is important for counseling women about reproductive planning as well as for treatment planning for women experiencing hormone-sensitive gynecological conditions such as endometriosis and fibroids.

conclusionsAMH can be considered as an indicator of fertility in late reproductive age women and pregnancy outcome in assisted reproductive technology cycles. AMH can strongly predict poor response in the controlled ovarian stimulation.

Indexed as

Age FactorsAnti-Mullerian HormoneBiomarkersFemaleFertilityHumansPregnancyAnti-Mullerian HormoneBiomarkersAnti-Müllerian hormoneFertilityLate reproductive agePregnancy

Identifiers

PMID27300031
PMCPMC5069312
OpenAlexW2427302098

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.