SynthesisBioMed research international2016
Prenatal Maternal Anxiety as a Risk Factor for Preterm Birth and the Effects of Heterogeneity on This Relationship: A Systematic Review and Meta-Analysis.
Synthesis in BioMed research international, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
41 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Epigenome-wide association studies of prenatal maternal mental health and infant epigenetic profiles: a systematic review.Translational psychiatry · 2023Pooled it
- Pregnancy and Delivery Outcomes Following Benzodiazepine Exposure: A Systematic Review and Meta-analysis.Canadian journal of psychiatry. Revue canadienne de psychiatrie · 2020Pooled it
- Identifying psychosocial predictors and developing a risk score for preterm birth among Kenyan pregnant women.BMC pregnancy and childbirth · 2025Trial
- Effect of cognitive behavioral therapy-based counseling on perceived stress in pregnant women with history of primary infertility: a controlled randomized clinical trial.BMC psychiatry · 2021Trial
- Integrating NRG1 and OXT Polymorphisms, Maternal Psychological Vulnerability, and Obstetric-Neonatal Outcomes: A Genotype-Phenotype Pilot Study.Journal of clinical medicine · 2026Article
- Psychological Vulnerability During Pregnancy and Its Obstetric Consequences: A Multidimensional Approach.Healthcare (Basel, Switzerland) · 2025Article
- Changes in Preterm and Low Birthweight Birth Rate During the COVID-19 Lockdown at Two San Francisco Hospitals.Journal of epidemiology and global health · 2025Article
- Food insecurity during pregnancy and associated perinatal outcomes: a scoping review.Epidemiologic reviews · 2025Article
- Impact of prenatal anxiety on pregnancy outcome among women in Baghdad teaching hospitals.Journal of education and health promotion · 2025Article
- The association between pre-pregnancy and first-trimester hair cortisol and preterm birth: a causal inference model.European journal of epidemiology · 2024Article
- Accelerating adverse pregnancy outcomes research amidst rising medication use: parallel retrospective cohort analyses for signal prioritization.BMC medicine · 2024Article
- Digital Health as a Mechanism to Reduce Neonatal Intensive Care Unit Admissions: Retrospective Cohort Study.JMIR pediatrics and parenting · 2024Article
- Recalled Maternal Rearing Behaviour of Individuals Born Preterm and Their Mothers: The Impact of Intimate Mother-Child Contact.Journal of clinical medicine · 2024Article
- Impact of unplanned pregnancy on neonatal outcomes: findings of new high-risk newborns in Peru.International health · 2024Article
- Node embedding-based graph autoencoder outlier detection for adverse pregnancy outcomes.Scientific reports · 2023Article
- Evaluation of factors related to maternal anxiety during pregnancy among women referred to Tabriz primary care centers.BMC psychiatry · 2023Article
- Individual and collective contribution of antenatal psychosocial distress conditions and preterm birth in Pakistani women.PloS one · 2023Article
- Giving Birth in the Early Phases of the COVID-19 Pandemic: The Patient Experience.Maternal and child health journal · 2022Article
- Is it Necessary to Evaluate Fear of Childbirth in Pregnant Women? A Scoping Review.Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia · 2022Article
- Maternal adverse childhood experiences and their association with preterm birth: secondary analysis of data from universal health visiting.BMC pregnancy and childbirth · 2022Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background. Systematic reviews (SR) and meta-analyses (MA) that previously explored the relationship between prenatal maternal anxiety (PMA) and preterm birth (PTB) have not been comprehensive in study inclusion, failing to account for effects of heterogeneity and disagree in their conclusions. Objectives. This SRMA provides a summary of the published evidence of the relationship between PMA and PTB while examining methodological and statistical sources of heterogeneity. Methods. Published studies from MEDLINE, CINAHL, PsycINFO, and EMBASE, until June 2015, were extracted and reviewed. Results. Of the 37 eligible studies, 31 were used in this MA; six more were subsequently excluded due to statistical issues, substantially reducing the heterogeneity. The odds ratio for PMA was 1.70 (95% CI 1.33, 2.18) for PTB and 1.67 (95% CI 1.35, 2.07) for spontaneous PTB comparing higher levels of anxiety to lower levels. Conclusions. Consistent findings indicate a significant association between PMA and PTB. Due to the statistical problem of including collinear variables in a single regression model, it is hard to distinguish the effect of the various types of psychosocial distress on PTB. However, a prenatal program aimed at addressing mental health issues could be designed and evaluated using a randomised controlled trial to assess the causal nature of different aspects of mental health on PTB.
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