Evidence map›Paper›PMID 27298715›Full record

ArticleWorld journal of gastrointestinal endoscopy2016

Low volume polyethylene glycol with ascorbic acid, sodium picosulfate-magnesium citrate, and clear liquid diet alone prior to small bowel capsule endoscopy.

Erin Rayner-Hartley, Majid Alsahafi, Paula Cramer, Nazira Chatur, Fergal Donnellan

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in World journal of gastrointestinal endoscopy, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.0field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 3 countries.

Erin Rayner-HartleyErin Rayner-Hartley, Majid Alsahafi, Paula Cramer, Nazira Chatur, Fergal Donnellan, Division of Gastroenterology, Vancouver General Hospital, University of British Columbia, Vancouver, British Columbia V6Z3H8, Canada.
Majid AlsahafiErin Rayner-Hartley, Majid Alsahafi, Paula Cramer, Nazira Chatur, Fergal Donnellan, Division of Gastroenterology, Vancouver General Hospital, University of British Columbia, Vancouver, British Columbia V6Z3H8, Canada.
Paula CramerErin Rayner-Hartley, Majid Alsahafi, Paula Cramer, Nazira Chatur, Fergal Donnellan, Division of Gastroenterology, Vancouver General Hospital, University of British Columbia, Vancouver, British Columbia V6Z3H8, Canada.
Nazira ChaturErin Rayner-Hartley, Majid Alsahafi, Paula Cramer, Nazira Chatur, Fergal Donnellan, Division of Gastroenterology, Vancouver General Hospital, University of British Columbia, Vancouver, British Columbia V6Z3H8, Canada.
Fergal DonnellanErin Rayner-Hartley, Majid Alsahafi, Paula Cramer, Nazira Chatur, Fergal Donnellan, Division of Gastroenterology, Vancouver General Hospital, University of British Columbia, Vancouver, British Columbia V6Z3H8, Canada.
University Gastroenterology · USKing Abdulaziz University · SAUniversity of British Columbia · CAVancouver General Hospital · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo compare low volume polyethylene glycol with ascorbic acid, sodium picosulfate-magnesium citrate and clear liquid diet alone as bowel preparation prior to small bowel capsule endoscopy (CE).

methodsWe retrospectively collected all CE studies done from December 2011 to July 2013 at a single institution. CE studies were reviewed only if low volume polyethylene glycol with ascorbic acid, sodium picosulfate-magnesium citrate or clear liquid diet alone used as the bowel preparation. The studies were then reviewed by the CE readers who were blinded to the preparation type. Cleanliness and bubble burden were graded independently within the proximal, middle and distal small bowel using a four-point scale according to the percentage of small bowel mucosa free of debris/bubbles: grade 1 = over 90%, grade 2 = between 90%-75%, grade 3 = between 50%-75%, grade 4 = less than 50%. Data are expressed as mean ± SEM. ANOVA and Fishers exact test were used where appropriate. P values < 0.05 were considered statistically significant.

resultsA of total of 123 CE studies were reviewed. Twenty-six studies were excluded from analysis because of incomplete small bowel examination. In the remaining studies, 39 patients took low volume polyethylene glycol with ascorbic acid, 31 took sodium picosulfate-magnesium citrate and 27 took a clear liquid diet alone after lunch on the day before CE, followed by overnight fasting in all groups. There was no significant difference in small bowel cleanliness (1.98 ± 0.09 vs 1.84 ± 0.08 vs 1.76 ± 0.08) or small bowel transit time (213 ± 13 vs 248 ± 14 ± 225 ± 19 min) for clear liquid diet alone, MoviPrep and Pico-Salax respectively. The bubble burden in the mid small bowel was significantly higher in the MoviPrep group (1.6 ± 0.1 vs 1.9 ± 0.1 vs 1.6 ± 0.1, P < 0.05). However this did not result in a significant difference in diagnosis of pathology.

conclusionThere was no significant difference in small bowel cleanliness or diagnostic yield of small bowel CE between the three preparations regimens used in this study.

Indexed as

Bowel preparationCapsule endoscopyPolyethylene glycolSmall bowelSodium picosulfate

Identifiers

PMID27298715
PMCPMC4896905
OpenAlexW2463397155

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.