Evidence map›Paper›PMID 27298612›Full record

ArticleEXCLI journal2013

Selenoprotein M is expressed during bone development.

Melanie Grosch, Jennifer Fuchs, Michael Bösl, Andreas Winterpacht, Andreas Tagariello

Open access · greenAbstract read
PubMed Full text at PMC
In one paragraph

Article in EXCLI journal, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact, top 70% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Deciphering the Role of Selenoprotein M.Antioxidants (Basel, Switzerland) · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Melanie GroschInstitute of Human Genetics, University Hospital Erlangen, University of Erlangen-Nürnberg, Erlangen, Germany.
Jennifer FuchsInstitute of Human Genetics, University Hospital Erlangen, University of Erlangen-Nürnberg, Erlangen, Germany.
Michael BöslMax Planck Institute of Neurobiology, Martinsried, Germany.
Andreas WinterpachtInstitute of Human Genetics, University Hospital Erlangen, University of Erlangen-Nürnberg, Erlangen, Germany.
Andreas TagarielloInstitute of Human Genetics, University Hospital Erlangen, University of Erlangen-Nürnberg, Erlangen, Germany.
Max Planck Institute of Neurobiology · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

25 selenoproteins that contain selenium, incorporated as selenocysteine (Sec), have been identified to date. Selenoprotein M (SELM) is one of seven endoplasmic reticulum (ER)-resident, Sec-containing proteins that may be involved in posttranslational processing of proteins and maintenance of ER function. Since SELM was overrepresented in a cartilage- and bone-specific expressed sequence tag (EST) library, we further investigated the expression pattern of Selm and its possible biological function in the skeleton. RNA in situ hybridization of Selm in chicken and mice of different developmental stages revealed prominent expression in bones, specifically in osteoblast, and in tendons. This result suggests that SELM functions during bone development, where it is possibly involved in the processing of secreted proteins.

Indexed as

bone developmentKashin-Beck osteoarthropathyseleniumselenoproteinsthiol-disulfide oxidoreductaseunfolded protein response

Identifiers

PMID27298612
PMCPMC4904744
OpenAlexW2472877107

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.