Evidence map›Paper›PMID 27297740›Full record

Trial reportPublic health nutrition2017

Influence of an intervention targeting a reduction in sugary beverage intake on the δ13C sugar intake biomarker in a predominantly obese, health-disparate sample.

Brenda M Davy, A Hope Jahren, Valisa E Hedrick, Wen You, Jamie M Zoellner

Open access · bronzeAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Public health nutrition, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 1 pooled it
1.8field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 1 synthesis or guideline pooled it, 32 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Brenda M Davy1Department of Human Nutrition,Foods and Exercise,Virginia Polytechnic Institute and State University,295 West Campus Drive,221 Wallace Hall (0430),Blacksburg,VA 24061,USA.
A Hope Jahren2School of Earth and Ocean Science and Technology,University of Hawai'i at Manoa,HI,USA.
Valisa E Hedrick1Department of Human Nutrition,Foods and Exercise,Virginia Polytechnic Institute and State University,295 West Campus Drive,221 Wallace Hall (0430),Blacksburg,VA 24061,USA.
Wen You3Department of Agricultural and Applied Economics,Virginia Polytechnic Institute and State University,Blacksburg,VA,USA.
Jamie M Zoellner1Department of Human Nutrition,Foods and Exercise,Virginia Polytechnic Institute and State University,295 West Campus Drive,221 Wallace Hall (0430),Blacksburg,VA 24061,USA.
Virginia Tech · USUniversity of Hawaiʻi at Mānoa · US

Funding

SIPsmartER: A nutrition literacy approach to reducing sugar-sweetened beveragesR01CA154364 · NCI · VIRGINIA POLYTECHNIC INST AND ST UNIV · PI ZOELLNER, JAMIE · 2011 to 2015
$2.8M
NCI NIH HHS R01 CA154364
6 · The paper itself

Abstract

objectiveControversy exists surrounding the health effects of added sugar (AS) and sugar-sweetened beverage (SSB) intakes, primarily due to a reliance on self-reported dietary intake. The purpose of the current investigation was to determine if a 6-month intervention targeting reduced SSB intake would impact δ13C AS intake biomarker values.

designA randomized controlled intervention trial. At baseline and at 6 months, participants underwent assessments of anthropometrics and dietary intake. Fasting fingerstick blood samples were obtained and analysed for δ13C value using natural abundance stable isotope MS. Statistical analysis included descriptive statistics, correlational analyses and multilevel mixed-effects linear regression analysis using an intention-to-treat approach.

settingRural Southwest Virginia, USA. SUBJECTS: Adults aged ≥18 years who consumed ≥200 kcal SSB/d (≥837 kJ/d) were randomly assigned to either the intervention (n 155) or a matched-contact group (n 146). Participants (mean age 42·1 (sd 13·4) years) were primarily female and overweight (21·5 %) or obese (57·0 %).

resultsA significant group by time difference in δ13C value was detected (P<0·001), with mean (sd) δ13C value decreasing in the intervention group (pre: -18·92 (0·65) ‰, post: -18·97 (0·65) ‰) and no change in the comparison group (pre: -18·94 (0·72) ‰, post: -18·92 (0·73) ‰). Significant group differences in weight and BMI change were also detected. Changes in biomarker δ13C values were consistent with changes in self-reported AS and SSB intakes.

conclusionsThe δ13C sugar intake biomarker assessed using fingerstick blood samples shows promise as an objective indicator of AS and SSB intakes which could be feasibly included in community-based research trials.

Indexed as

AdultBeveragesBiomarkersBody Mass IndexCarbon IsotopesDietDietary SugarsFemaleHumansMaleMiddle AgedNutritive SweetenersObesityOverweightRural PopulationVirginiaBiomarkersCarbon IsotopesDietary SugarsNutritive SweetenersAdded sugarDietary assessmentDietary biomarkerIsotopeSugar-sweetened beverage

Identifiers

PMID27297740
PMCPMC5576149
OpenAlexW2423597161

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.