Evidence map›Paper›PMID 27297680›Full record

SynthesisEuropean urology2016

Enhanced Recovery Pathways Versus Standard Care After Cystectomy: A Meta-analysis of the Effect on Perioperative Outcomes.

Mark D Tyson, Sam S Chang

2 registry-linked trialsOpen access · greenAbstract readComparative StudyMeta-AnalysisSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in European urology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 83 papers, 11 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
83citing papers in PubMed, 11 pooled it
26.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03960697 naunknown statusnot on this mapstarted 2019, after this paper: background citation

Effects of Walking Out From Operating Room on Postoperative Recovery of Patients Undergoing Laparoscopic Total or Partial Nephrectomy

TypeinterventionalSponsorSixth Affiliated Hospital, Sun Yat-sen UniversityRan2019 to 2023Enrolled182ConditionsLaparoscopic Nephrectomy, Enhanced Recovery After SurgeryArmswalk out from operating room
NCT04576533 naunknown statusnot on this mapstarted 2020, after this paper: background citation

Effects of Walking Out From Operating Room on Postoperative Recovery of Patients Undergoing Laparoscopic Colorectal Surgery

TypeinterventionalSponsorSixth Affiliated Hospital, Sun Yat-sen UniversityRan2020 to 2025Enrolled300ConditionsEnhanced Recovery After SurgeryArmswalk out from operating room
3 · Its place in the literature

Who cites it

83 citing papers in PubMed, 11 syntheses or guidelines pooled it, 212 citations in OpenAlex.

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  6. [Enhanced recovery after surgery-Does the ERAS concept keep its promises].Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen · 2021
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23 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Mark D TysonDepartment of Urology, Mayo Clinic Hospital, Phoenix, AZ, USA; Department of Urologic Surgery, Vanderbilt University Medical Center, Nashville, TN, USA. Electronic address: tyson.mark@mayo.edu.
Sam S ChangDepartment of Urologic Surgery, Vanderbilt University Medical Center, Nashville, TN, USA.
Mayo Clinic Hospital · USVanderbilt University Medical Center · US

Funding

Surgical Oncology Training GrantT32CA106183 · NCI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI James Richard Goldenring · 2004 to 2026
$6.0M
NCI NIH HHS T32 CA106183
6 · The paper itself

Abstract

contextEnhanced recovery after surgery (ERAS) protocols aim to improve surgical outcomes by reducing variation in perioperative best practices. However, among published studies, results show a striking variation in the effect of ERAS pathways on perioperative outcomes after cystectomy.

objectiveTo perform a systematic review of the literature and a meta-analysis comparing the effectiveness of ERAS versus standard care on perioperative outcomes after cystectomy. EVIDENCE ACQUISITION: We performed a literature search of PubMed, EMBASE, Web of Science, Google Scholar, the Cochrane Library, and the health-related grey literature in February 2016 according to the Preferred Reporting Items for Systematic Review and Meta-analysis and the Cochrane Handbook. Studies were reviewed according to criteria from the Oxford Centre for Evidence-Based Medicine. Thirteen studies (1493 total patients) met the inclusion criteria (ERAS: 801, standard care: 692). A pooled meta-analysis of all comparative studies was performed using inverse-weighted, fixed-effects models, and random-effects models. Publication bias was graphically assessed using contour-enhanced funnel plots and was formally tested using the Harbord modification of the Egger test. EVIDENCE SYNTHESIS: Pooled data showed a lower overall complication rate (risk ratio [RR]: 0.85, 95% confidence interval [CI]: 0.74-0.97, p = 0.017, I

conclusionsERAS protocols reduce the length of stay, time-to-bowel function, and rate of complications after cystectomy. PATIENT SUMMARY: Enhanced recovery after surgery pathways for cystectomy reduce complications and the amount of time patients spend in the hospital.

Indexed as

Standard of CareCritical PathwaysCystectomyHumansLength of StayPostoperative CarePostoperative ComplicationsUrinary Bladder NeoplasmsUrinary DiversionClinical pathwaysCollaborative careCystectomyEnhanced recoveryFast track

Identifiers

PMID27297680
PMCPMC5149115
OpenAlexW2410154863

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.