ArticleScientific reports2016
Surfactant-activated lipase hybrid nanoflowers with enhanced enzymatic performance.
Article in Scientific reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.
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The trial behind it
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Who cites it
31 citing papers in PubMed, 173 citations in OpenAlex.
- Inorganic Hybrid Nanoflower Patterns of Transglycosylating α-glucosidase for Production of Isomaltooligosaccharides.Applied biochemistry and biotechnology · 2026Article
- Enhanced Catalytic Performance and Stability of Sucrose Isomerase Via CuApplied biochemistry and biotechnology · 2026Review
- Copper doped hybrid nanosponges functionalized with Aplysina aerophoba extract for enhanced bioactive performance.Scientific reports · 2026Article
- Nanoflowers: Smart Molecules for Biofilm Management.Applied biochemistry and biotechnology · 2025Review
- Effectiveness of polyethylene glycol and glutaraldehyde as enhancers for lipase-immobilized hybrid organic-inorganic nanoflowers.Bioprocess and biosystems engineering · 2025Article
- Synthesis with control of DNA nanoflowers towards biomedical applications.Materials today. Bio · 2025Review
- Development of a robust enzyme cascade system: co-immobilization of laccase and versatile peroxidase on polyacrylamide hydrogel for enhanced BPA degradation.Biodegradation · 2025Article
- A Cofactor Regeneration System for 2-Aminobutyric Acid Production Based on Combined Cross-Linked Enzyme Aggregates: Utilizing His-Tagged Enzymes With Low-Concentration Calcium Ions as Precipitant.Engineering in life sciences · 2025Article
- Immobilization ofEngineering microbiology · 2024Article
- Evaluation of the Antimicrobial Activity of Triple Enzyme-Embedded Organic-Inorganic Hybrid Nanoflowers (hNFs) in Comparison with Powerful Antimicrobial Agent Chitosan.Current microbiology · 2024Article
- Co-administration of xylo-oligosaccharides produced by immobilized Aspergillus terreus xylanase with carbimazole to mitigate its adverse effects on the adrenal gland.Scientific reports · 2024Article
- The Formation of D-Allulose 3-Epimerase Hybrid Nanoflowers and Co-Immobilization on Resins for Improved Enzyme Activity, Stability, and Processability.International journal of molecular sciences · 2024Article
- Functionalized magnetic lipase/CuHeliyon · 2024Article
- Experimental and Computational Analysis of Synthesis Conditions of Hybrid Nanoflowers for Lipase Immobilization.Molecules (Basel, Switzerland) · 2024Article
- Novel biocatalysts based on enzymes in complexes with nano- and micromaterials.Biophysical reviews · 2023Review
- Cu-HKUST-1 and Hydroxyapatite-The Interface of Two Worlds toward the Design of Functional Materials Dedicated to Bone Tissue Regeneration.ACS biomaterials science & engineering · 2023Article
- Bioinspired Framework Catalysts: From Enzyme Immobilization to Biomimetic Catalysis.Chemical reviews · 2023Review
- Tuning Immobilized Enzyme Features by Combining Solid-Phase Physicochemical Modification and Mineralization.International journal of molecular sciences · 2022Article
- Recent advancements in enzyme-incorporated nanomaterials: Synthesis, mechanistic formation, and applications.Biotechnology and bioengineering · 2022Review
- Preparation, characterization and stability of cross linked nitrilase aggregates (nitrilase-CLEAs) for hydroxylation of 2-chloroisonicotinonitrile to 2-chloroisonicotinic acid.Bioprocess and biosystems engineering · 2022Article
Corrections and comments
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Authors and funding
5 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Increasing numbers of materials have been extensively used as platforms for enzyme immobilization to improve catalytic performance. However, activity of the most of the enzymes was declined after immobilization. Here, we develop a surfactant-activated lipase-inorganic flowerlike hybrid nanomaterials with rational design based on interfacial activation and self-assembly. The resulting surfactant-activated lipase-inorganic hybird nanoflower (activated hNF-lipase) exhibited 460% and 200% higher activity than native lipase and conventional lipase-inorganic hybird nanoflower (hNF-lipase). Furthermore, the activated hNF-lipase displayed good reusability due to its monodispersity and mechanical properties, and had excellent long-time stability. The superior catalytic performances were attributed to both the conformational modulation of surfactants and hierarchical structure of nanoflowers, which not only anchored lipases in an active form, but also decreased the enzyme-support negative interaction and mass-transfer limitations. This new biocatalytic system is promising to find widespread use in applications related to biomedicine, biosensor, and biodiesel.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.