Evidence map›Paper›PMID 27297097›Full record

Trial reportPsycho-oncology2017

Psychosocial morbidity in women with abnormal cervical cytology managed by cytological surveillance or initial colposcopy: longitudinal analysis from the TOMBOLA randomised trial.

S Fielding, K Rothnie, N M Gray, J Little, M E Cruickshank, K Neal, L G Walker, D Whynes, S C Cotton, L Sharp and 1 more

Abstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Psycho-oncology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Trial
  2. Observational
  3. Review
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

S FieldingMedical Statistics Team, Division of Applied Health Sciences, University of Aberdeen, Aberdeen, Scotland.
K RothnieFaculty of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine and Faculty of Medicine, Imperial College London, London, UK.
N M GrayScottish Improvement Science Collaborating Centre, School of Nursing and Health Sciences, University of Dundee, Dundee, Scotland.
J LittleSchool of Epidemiology, Public Health and Preventive Medicine, University of Ottawa, Ottawa, Canada.
M E CruickshankDivision of Medical and Dental Education, University of Aberdeen, Aberdeen, Scotland.
K NealConsultant Epidemiologist, London and South East PHE Centres, London, UK.
L G WalkerMedical Research Centre, University of Hull, Hull, UK.
D WhynesSchool of Economics, University of Nottingham, Nottingham, UK.
S C CottonDivision of Applied Health Sciences, University of Aberdeen, Aberdeen, UK.
L SharpInstitute of Health & Society, Newcastle University, Newcastle, UK.
In association with the TOMBOLA group

Funding

Medical Research Council G9700808
6 · The paper itself

Abstract

objectiveTo compare psychosocial outcomes (follow-up related worries and satisfaction with follow-up related information and support) over 30 months of two alternative management policies for women with low-grade abnormal cervical cytology.

methodsWomen aged 20-59 years with low-grade cytological abnormalities detected in the National Health Service Cervical Screening Programme were randomised to cytological surveillance or initial colposcopy. A total of 3399 women who completed psychosocial questionnaires at recruitment were invited to complete questionnaires at 12, 18, 24 and 30 months. Linear mixed models were used to investigate differences between arms in the two psychosocial outcomes. Each outcome had a maximum score of 100, and higher scores represented higher psychosocial morbidity.

resultsOn average, over 30 months, women randomised to colposcopy scored 2.5 points (95%CI -3.6 to -1.3) lower for follow-up related worries than women randomised to cytological surveillance. Women in the colposcopy arm also scored significantly lower for follow-up related satisfaction with information and support (-2.4; -3.3 to -1.4) over 30 months. For both outcomes, the average difference between arms was greatest at 12th- and 18th-month time points. These differences remained when the analysis was stratified by post-school education.

conclusionsWomen with low-grade cytology, irrespective of their management, have substantial initial psychosocial morbidity that reduces over time. Implementation of newer screening strategies, which include surveillance, such as primary HPV screening, need to consider the information and support provided to women. © 2016 The Authors. Psycho-Oncology published by John Wiley & Sons Ltd.

Indexed as

AdultAnxietyColposcopyCytodiagnosisFemaleHumansLongitudinal StudiesMiddle AgedMorbiditySurveys and QuestionnairesUterine Cervical DysplasiaUterine Cervical NeoplasmsYoung Adultcancercolposcopycytologyoncologypsychosocial morbidity

Identifiers

PMID27297097
PMCPMC5412834

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.