Evidence map›Paper›PMID 27296940›Full record

ArticleThe American journal of gastroenterology2016

Predictive Factors for Differentiating Between Crohn's Disease and Intestinal Tuberculosis in Koreans.

Yunho Jung, Young Hwangbo, Soon Man Yoon, Hoon Sup Koo, Hyun Deok Shin, Jeong Eun Shin, Hee Seok Moon, Sang Bum Kang, Jeong Rok Lee, Kyu Chan Huh

Abstract read
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In one paragraph

Article in The American journal of gastroenterology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
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  3. Gastrointestinal tuberculosis: A systematic review of epidemiology, presentation, diagnosis and treatment.Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association
    Pooled it
  4. Review
  5. Identification of Potential Functional Modules and Diagnostic Genes for Crohn's Disease Based on Weighted Gene Co-expression Network Analysis and LASSO Algorithm.The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology · 2025
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  20. Performance of Diagnostic Model for Differentiating Between COVID-19 and Influenza: A 2-Center Retrospective Study.Medical science monitor : international medical journal of experimental and clinical research · 2021
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors.

Yunho JungDepartment of Internal Medicine, Soonchunhyang University College of Medicine, Cheonan-si, Chungcheongnam-do, South Korea.
Young HwangboDepartment of Preventive Medicine, Soonchunhyang University College of Medicine, Cheonan-si, Chungcheongnam-do, South Korea.
Soon Man YoonDepartment of Internal Medicine, Chungbuk National University Hospital, Cheongju-si, Chungcheongbuk-do, South Korea.
Hoon Sup KooDepartment of Internal Medicine, Konyang University of Medicine, Daejeon, South Korea.
Hyun Deok ShinDepartment of Internal Medicine, Dankook University College of Medicine, Cheonan-si, Chungcheongnam-do, South Korea.
Jeong Eun ShinDepartment of Internal Medicine, Dankook University College of Medicine, Cheonan-si, Chungcheongnam-do, South Korea.
Hee Seok MoonDepartment of Internal Medicine, Chungnam National University Hospital, Daejeon, South Korea.
Sang Bum KangDepartment of Internal Medicine, Daejeon St Mary's Hospital, College of Medicine, Daejeon, South Korea.
Jeong Rok LeeDepartment of Internal Medicine, Konkuk University School of Medicine, Chungju-si, Chungcheongbuk-do, South Korea.
Kyu Chan HuhDepartment of Internal Medicine, Konyang University of Medicine, Daejeon, South Korea.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesA differential diagnosis between intestinal tuberculosis (ITB) and Crohn's disease (CD) is challenging. The aim of this study was to investigate the clinical, endoscopic, and histological features and to create a predictive score model for differentiating CD and ITB.

methodsIn total, 261 patients, 99 with ITB and 162 with CD, were recruited from seven tertiary centers from 2005 to 2013 and reviewed retrospectively. For the creation of a validated model, parameters were selected by univariate logistic regression and receiver operating characteristic curve analyses. Then, the prediction model was established on the basis of β-coefficients of the multivariate logistic regression. For the validation of the model, the same regression equation was tested on the other group.

resultsAge, diarrhea, ring-shaped ulcer, longitudinal ulcer, sigmoid involvement, suspicious radiological pulmonary tuberculosis, and gender were selected as the factors for a seven-marker model. In the seven-marker model of the validation data set, the sensitivity, specificity, positive predictive value, and negative predictive value with a cutoff level of 0.35 were 98.0, 92.4, 88.9, and 98.6, respectively.

conclusionsThe seven-marker model seems to be highly reliable for differentiating between ITB and CD and could be conveniently used by clinicians to obtain results.

Indexed as

Abdominal PainAdolescentAdultAgedAge FactorsAnus DiseasesColonoscopyCrohn DiseaseDiagnosis, DifferentialDiarrheaFemaleHumansLogistic ModelsMaleMiddle AgedRadiography, Thoracic

Identifiers

PMID27296940

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.