Evidence map›Paper›PMID 27295281›Full record

ArticleInternational journal of environmental health research

Medication use associated with exposure to manganese in two Ohio towns.

Rosemarie M Bowler, Shane W Adams, Chris W Wright, Yangho Kim, Andrew Booty, Michelle Colledge, Vihra V Gocheva, Danelle T Lobdell

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of environmental health research. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Rosemarie M Bowlera Department of Psychology , San Francisco State University , San Francisco , CA , USA.
Shane W Adamsa Department of Psychology , San Francisco State University , San Francisco , CA , USA.
Chris W Wrighta Department of Psychology , San Francisco State University , San Francisco , CA , USA.
Yangho Kimb Department of Occupational and Environmental Medicine , Ulsan University Hospital, University of Ulsan College of Medicine , Ulsan , South Korea.
Andrew Bootyc Department of Psychiatry , University of California San Francisco , San Francisco , CA , USA.
Michelle Colledged ATSDR , Chicago , IL , USA.
Vihra V Gochevaa Department of Psychology , San Francisco State University , San Francisco , CA , USA.
Danelle T Lobdelle National Health and Environmental Effects Research Laboratory , U.S. EPA , Research Triangle Park , NC , USA.

Funding

Intramural CDC HHS CC999999
6 · The paper itself

Abstract

This report describes the use of medications as a proxy when medical record reviews are unavailable, to study the health effects of residents environmentally exposed to air-manganese (n = 185) compared to unexposed residents (n = 90). Participants' current medication lists and medication questionnaire responses were collected in clinical interviews and categorized into 13 domains. Exposed participants reported fewer hours of sleep than controls (6.6 vs. 7.0). The exposed used significantly more medications than unexposed participants (82.2 % vs. 67.8 %) and, when adjusting for age, education, and personal income, also for pain (aOR = 2.40) and hypothyroidism (aOR = 7.03). Exposed participants with higher air-Mn concentrations, monitored for 10 years by the U.S. Environmental Protection Agency, were 1.5 times more likely to take pain medications. The exposed participants take significantly more medications than unexposed participants in the categories of hypothyroidism, pain, supplements, and total medications.

Indexed as

Environmental ExposureAdultAgedAir PollutantsDrug UtilizationEnvironmental MonitoringFemaleHumansMaleManganeseMiddle AgedModels, TheoreticalNonprescription DrugsOhioPlant PreparationsPrescription DrugsAir PollutantsManganeseNonprescription DrugsPlant PreparationsPrescription DrugsAircommunitiesheavy metalsillnesspollution

Identifiers

PMID27295281
PMCPMC5583632

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.