Evidence map›Paper›PMID 27295184›Full record

ReviewAnnals of biomedical engineering2017

3D-Printing Technologies for Craniofacial Rehabilitation, Reconstruction, and Regeneration.

Ethan L Nyberg, Ashley L Farris, Ben P Hung, Miguel Dias, Juan R Garcia, Amir H Dorafshar, Warren L Grayson

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Annals of biomedical engineering, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 80 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
80citing papers in PubMed, 1 pooled it
6.6field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

80 citing papers in PubMed, 1 synthesis or guideline pooled it, 221 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Review
  6. Effect of artificial aging on fracture toughness and hardness of 3D-printed and milled 3Y-TZP zirconia.Journal of prosthodontics : official journal of the American College of Prosthodontists · 2025
    Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Review
  13. Article
  14. Article
  15. Review
  16. Review
  17. 3D printed OActa biomaterialia · 2024
    Article
  18. Bone reconstruction using CAD/CAM technology in head and neck surgical oncology. A narrative review of state of the art and aesthetic-functional outcomes.Acta otorhinolaryngologica Italica : organo ufficiale della Societa italiana di otorinolaringologia e chirurgia cervico-facciale · 2024
    Review
  19. 3D Printing for the Development of Palatal Defect Prosthetics.Federal practitioner : for the health care professionals of the VA, DoD, and PHS · 2024
    Article
  20. Recent advances in additive manufacturing of patient-specific devices for dental and maxillofacial rehabilitation.Dental materials : official publication of the Academy of Dental Materials · 2024
    Review

20 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Ethan L NybergDepartment of Biomedical Engineering, Translational Tissue Engineering Center, Johns Hopkins University School of Medicine, 400 N. Broadway, Smith 5023, Baltimore, MD, 21231, USA.
Ashley L FarrisDepartment of Biomedical Engineering, Translational Tissue Engineering Center, Johns Hopkins University School of Medicine, 400 N. Broadway, Smith 5023, Baltimore, MD, 21231, USA.
Ben P HungDepartment of Biomedical Engineering, Translational Tissue Engineering Center, Johns Hopkins University School of Medicine, 400 N. Broadway, Smith 5023, Baltimore, MD, 21231, USA.
Miguel DiasDepartment of Biomedical Engineering, Translational Tissue Engineering Center, Johns Hopkins University School of Medicine, 400 N. Broadway, Smith 5023, Baltimore, MD, 21231, USA.
Juan R GarciaDepartment of Art as Applied to Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Amir H DorafsharDepartment of Plastic and Reconstructive Surgery, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Warren L GraysonDepartment of Biomedical Engineering, Translational Tissue Engineering Center, Johns Hopkins University School of Medicine, 400 N. Broadway, Smith 5023, Baltimore, MD, 21231, USA. wgrayson@jhmi.edu.ORCID 0000-0001-6099-6469
Johns Hopkins University · US

Funding

Three-dimensional printing of native bone matrixF31DE024922 · NIDCR · JOHNS HOPKINS UNIVERSITY · PI HUNG, BEN PEN JUI · 2014 to 2015
$79k
NIDCR NIH HHS F31 DE024922
6 · The paper itself

Abstract

The treatment of craniofacial defects can present many challenges due to the variety of tissue-specific requirements and the complexity of anatomical structures in that region. 3D-printing technologies provide clinicians, engineers and scientists with the ability to create patient-specific solutions for craniofacial defects. Currently, there are three key strategies that utilize these technologies to restore both appearance and function to patients: rehabilitation, reconstruction and regeneration. In rehabilitation, 3D-printing can be used to create prostheses to replace or cover damaged tissues. Reconstruction, through plastic surgery, can also leverage 3D-printing technologies to create custom cutting guides, fixation devices, practice models and implanted medical devices to improve patient outcomes. Regeneration of tissue attempts to replace defects with biological materials. 3D-printing can be used to create either scaffolds or living, cellular constructs to signal tissue-forming cells to regenerate defect regions. By integrating these three approaches, 3D-printing technologies afford the opportunity to develop personalized treatment plans and design-driven manufacturing solutions to improve aesthetic and functional outcomes for patients with craniofacial defects.

Indexed as

Bone RegenerationFacial InjuriesTissue EngineeringAnimalsFacial BonesHumansPlastic Surgery ProceduresPrinting, Three-Dimensional3D-printingCraniofacial implantsFacial prostheticsRegenerative medicineScaffoldsTissue engineering

Identifiers

PMID27295184
PMCPMC5154778
OpenAlexW2422189810

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.