Evidence map›Paper›PMID 27295115›Full record

ArticleEuropean child & adolescent psychiatry2017

Preschool hyperactivity specifically elevates long-term mental health risks more strongly in males than females: a prospective longitudinal study through to young adulthood.

Elizabeth Smith, Brenda J Meyer, Johanna Koerting, Cathy Laver-Bradbury, Louise Lee, Harriet Jefferson, Kapil Sayal, Luke Treglown, Margaret Thompson, Edmund J S Sonuga-Barke

Open access · hybridAbstract read
In one paragraph

Article in European child & adolescent psychiatry, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
5.3field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 28 citations in OpenAlex.

  1. Pathways to adaptive functioning in autism from early childhood to adolescence.Autism research : official journal of the International Society for Autism Research · 2022
    Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Attention-deficit hyperactivity disorder.Lancet (London, England) · 2020
    Review
  7. Article
  8. Anomalous Brain Development Is Evident in Preschoolers With Attention-Deficit/Hyperactivity Disorder.Journal of the International Neuropsychological Society : JINS · 2018
    Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 1 country.

Elizabeth SmithDepartment of Psychology, University of Bath, Bath, UK.
Brenda J MeyerDevelopmental Brain and Behaviour Laboratory, Psychology, University of Southampton, Southampton, SO17 1BJ, UK.
Johanna KoertingDevelopmental Brain and Behaviour Laboratory, Psychology, University of Southampton, Southampton, SO17 1BJ, UK.
Cathy Laver-BradburyDevelopmental Brain and Behaviour Laboratory, Psychology, University of Southampton, Southampton, SO17 1BJ, UK.
Louise LeeDevelopmental Brain and Behaviour Laboratory, Psychology, University of Southampton, Southampton, SO17 1BJ, UK.
Harriet JeffersonDevelopmental Brain and Behaviour Laboratory, Psychology, University of Southampton, Southampton, SO17 1BJ, UK.
Kapil SayalDivision of Psychiatry and Applied Psychology, School of Medicine, University of Nottingham, Nottingham, UK.
Luke TreglownDepartment of Psychology, University College London, London, UK.
Margaret ThompsonDevelopmental Brain and Behaviour Laboratory, Psychology, University of Southampton, Southampton, SO17 1BJ, UK.
Edmund J S Sonuga-BarkeDevelopmental Brain and Behaviour Laboratory, Psychology, University of Southampton, Southampton, SO17 1BJ, UK. ejb3@soton.ac.uk.
University of Southampton · GBSolent NHS Trust · GBUniversity College London · GBUniversity of Bath · GBUniversity of Nottingham · GB

Funding

Department of Health RP-PG-0108-10061
6 · The paper itself

Abstract

Evidence of continuities between preschool hyperactivity and adult mental health problems highlights the potential value of targeting early identification and intervention strategies. However, specific risk factors are currently unclear. This large-scale prospective longitudinal study aimed to identify which hyperactive preschoolers are at the greatest long-term risk of poor mental health. One hundred and seventy children (89 females) rated as hyperactive by their parents, and 88 non-hyperactive controls (48 females) were identified from a community sample of 4215 3-year-olds. Baseline data relating to behavioral/emotional problems and background characteristics were collected. Follow-up mental health and functional impairment outcomes were collected between 14 and 25 years of age. At age 3 years, males and females in the hyperactive group had similarly raised levels of hyperactivity and other behavior problems. In adolescence/young adulthood, these individuals showed elevated symptoms of ADHD, conduct disorder, mood disorder, anxiety and autism, as well as functional impairment. Preschool hyperactivity was strongly predictive of poor adolescent/adult outcomes for males across domains with effects being specifically driven by hyperactivity. For females, the effects of preschool hyperactivity were smaller and dropped to non-significant levels when other preschool problems were taken into account. Environmental risk factors also differed between the sexes, although these may also have been mediated by genetic risk. In conclusion, these results demonstrate marked sex differences in preschool predictors of later adolescent/adult mental health problems. Future research should include a measure of preschool inattention as well as hyperactivity. The findings highlight the potential value of tailored approaches to early identification strategies.

Indexed as

Sex CharacteristicsAdolescentAdultAge FactorsAnxietyAttention Deficit Disorder with HyperactivityChildChild, PreschoolCohort StudiesConduct DisorderFemaleHumansLongitudinal StudiesMaleMental HealthProspective StudiesLongitudinal studyLong-term riskMental healthPreschool hyperactivity

Identifiers

PMID27295115
PMCPMC5233734
OpenAlexW2411680216

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.