Evidence map›Paper›PMID 27294909›Full record

ReviewMolecules (Basel, Switzerland)2016

Antimicrobial Activity of Lactoferrin-Related Peptides and Applications in Human and Veterinary Medicine.

Natascia Bruni, Maria Teresa Capucchio, Elena Biasibetti, Enrica Pessione, Simona Cirrincione, Leonardo Giraudo, Antonio Corona, Franco Dosio

Open access · goldAbstract readReview
In one paragraph

Review in Molecules (Basel, Switzerland), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 105 papers.

0numbers the graph read from it
0cells of the map it votes in
105citing papers in PubMed
13.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

105 citing papers in PubMed, 225 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Review
  6. Review
  7. Article
  8. Article
  9. Article
  10. Review
  11. Review
  12. Review
  13. Article
  14. Review
  15. Article
  16. Article
  17. Article
  18. Review
  19. Review
  20. Identification and Characterization of a Novel GAPDH-Derived Antimicrobial Peptide From Jellyfish.Journal of peptide science : an official publication of the European Peptide Society · 2025
    Article

45 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Natascia BruniIstituto Farmaceutico Candioli, Beinasco (To) 10092, Italy. natascia.bruni@candioli.it.
Maria Teresa CapucchioDepartment of Veterinary Sciences, University of Torino, Torino 10095, Italy. mariateresa.capucchio@unito.it.
Elena BiasibettiDepartment of Veterinary Sciences, University of Torino, Torino 10095, Italy. elena.biasibetti@unito.it.
Enrica PessioneDepartment of Life Sciences and Systems Biology, University of Torino, Torino 10123, Italy. enrica.pessione@unito.it.
Simona CirrincioneDepartment of Life Sciences and Systems Biology, University of Torino, Torino 10123, Italy. simona.cirrincione@unito.it.
Leonardo GiraudoIstituto Farmaceutico Candioli, Beinasco (To) 10092, Italy. leonardo.giraudo@candioli.it.
Antonio CoronaAmbulatorio Veterinario Associato, Torino 10135, Italy. antonio@ambulatorioveterinario.eu.
Franco DosioDepartment of Drug Science and Technology, University of Torino, Torino 10125, Italy. franco.dosio@unito.it.
University of Turin · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Antimicrobial peptides (AMPs) represent a vast array of molecules produced by virtually all living organisms as natural barriers against infection. Among AMP sources, an interesting class regards the food-derived bioactive agents. The whey protein lactoferrin (Lf) is an iron-binding glycoprotein that plays a significant role in the innate immune system, and is considered as an important host defense molecule. In search for novel antimicrobial agents, Lf offers a new source with potential pharmaceutical applications. The Lf-derived peptides Lf(1-11), lactoferricin (Lfcin) and lactoferrampin exhibit interesting and more potent antimicrobial actions than intact protein. Particularly, Lfcin has demonstrated strong antibacterial, anti-fungal and antiparasitic activity with promising applications both in human and veterinary diseases (from ocular infections to osteo-articular, gastrointestinal and dermatological diseases).

Indexed as

Animal DiseasesAnimalsAnti-Infective AgentsAntimicrobial Cationic PeptidesEscherichia coliHumansLactoferrinVeterinary DrugsAnti-Infective AgentsAntimicrobial Cationic PeptidesLactoferrinVeterinary Drugsantimicrobial peptidesfood safetylactoferricinmilk proteins

Identifiers

PMID27294909
PMCPMC6273662
OpenAlexW2417653920

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.