ArticleJournal of racial and ethnic health disparities2016
Neighborhood Disadvantage and Cumulative Biological Risk Among a Socioeconomically Diverse Sample of African American Adults: An Examination in the Jackson Heart Study.
Article in Journal of racial and ethnic health disparities, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 55 papers, 1 of them a synthesis that pooled it.
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Who cites it
55 citing papers in PubMed, 1 synthesis or guideline pooled it, 87 citations in OpenAlex.
- Allostatic Load Measurement: A Systematic Review of Reviews, Database Inventory, and Considerations for Neighborhood Research.International journal of environmental research and public health · 2022Pooled it
- Buffering effects of protective factors on light and moderate-to-vigorous physical activity among african american women.Journal of behavioral medicine · 2023Trial
- Comprehensive examination of the multilevel adverse risk and protective factors for cardiovascular disease among hypertensive African Americans.Journal of clinical hypertension (Greenwich, Conn.) · 2019Trial
- Longitudinal Changes in Allostatic Load during a Randomized Church-based, Lifestyle Intervention in African American Women.Ethnicity & disease · 2019Trial
- Periconceptional neighborhood deprivation and risk of gestational and postpartum hypertensive disorders in a population-based cohort.American journal of preventive cardiology · 2026Article
- Explaining Racial and Ethnic Inequities in SARS-CoV-2-Related Outcomes: Results from a Serosurvey in Chicago.Journal of racial and ethnic health disparities · 2026Article
- Race and Risk: Disentangling the Racialized Distribution of Neighborhood Resources and Differential Health Risks in Southern U.S. Cities.Journal of racial and ethnic health disparities · 2026Article
- Neighborhood Disadvantage and Cardiovascular Mortality Among Colorectal Cancer Survivors.Cancers · 2025Article
- Neighborhood disadvantage and subjective cognitive function among older Black women.Psychology and aging · 2025Article
- Joint associations of pre-diabetes, pre-hypertension, and pre-dyslipidemia with cardiovascular and metabolic disease progression.Diabetology & metabolic syndrome · 2025Article
- Community-based stress, social support, and depressive symptoms among black adults: A mediation analysis.SSM. Mental health · 2025Article
- Disparities in cardiac arrest mortality among patients with chronic kidney disease: A US-based epidemiological analysis.Journal of arrhythmia · 2025Article
- Multilevel Mediators on the Associations of Neighborhood Social Environmental Factors and Severity of Metabolic Syndrome: The Jackson Heart Study.Journal of the American Heart Association · 2025Article
- Interplay of race and neighborhood deprivation on resting and ambulatory blood pressure in young adults.American journal of physiology. Heart and circulatory physiology · 2024Article
- Article
- Associations between dimensions of the social environment and cardiometabolic risk factors: Systematic review and meta-analysis.SSM - population health · 2024Review
- Estimation of place-based vulnerability scores for HIV viral non-suppression: an application leveraging data from a cohort of people with histories of using drugs.BMC medical research methodology · 2024Article
- Article
- The Maternal and Infant Environmental Health Riskscape study of perinatal disparities in greater Houston: rationale, study design and participant profiles.Frontiers in reproductive health · 2024Article
- Biological Age Mediates the Effects of Perceived Neighborhood Problems on Heart Failure Risk Among Black Persons.Journal of racial and ethnic health disparities · 2023Article
Corrections and comments
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Authors and funding
5 authors at 3 institutions in 1 country.
Funding
Abstract
objectivesNeighborhoods characterized by disadvantage influence multiple risk factors for chronic disease and are considered potential drivers of racial and ethnic health inequities in the USA. The objective of the present study was to examine the relationship between neighborhood disadvantage and cumulative biological risk (CBR) and the extent to which the association differs by individual income and education among a large, socioeconomically diverse sample of African American adults.
methodsData from the baseline examination of the Jackson Heart Study (2000-2004) were used for the analyses. The sample consisted of African American adults ages 21-85 with complete, geocoded data on CBR biomarkers and behavioral covariates (n = 4410). Neighborhood disadvantage was measured using a composite score of socioeconomic indicators from the 2000 US Census. Eight biomarkers representing cardiovascular, metabolic, inflammatory, and neuroendocrine systems were used to create a CBR score. We fit two-level linear regression models with random intercepts and included cross-level interaction terms between neighborhood disadvantage and individual socioeconomic status (SES).
resultsLiving in a disadvantaged neighborhood was associated with greater CBR after covariate adjustment (B = 0.18, standard error (SE) 0.07, p < 0.05). Interactions showed a weaker association for individuals with ≤high school education but were not statistically significant.
conclusionDisadvantaged neighborhoods contribute to poor health among African American adults via cumulative biological risk. Policies directly addressing the socioeconomic conditions of these environments should be considered as viable options to reduce disease risk in this group and mitigate racial/ethnic health inequities.
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