ArticleCancer causes & control : CCC2016
Dietary inflammatory index, Mediterranean diet score, and lung cancer: a prospective study.
Article in Cancer causes & control : CCC, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 69 papers, 9 of them syntheses that pooled it.
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Who cites it
69 citing papers in PubMed, 9 syntheses or guidelines pooled it, 127 citations in OpenAlex.
- Dietary Patterns and Risk of Lung Cancer: A Systematic Review and Meta-Analyses of Observational Studies.Current nutrition reports · 2023Pooled it
- Mediterranean Diet Patterns in Relation to Lung Cancer Risk: A Meta-Analysis.Frontiers in nutrition · 2022Pooled it
- An updated systematic review and meta-analysis on adherence to mediterranean diet and risk of cancer.European journal of nutrition · 2021Pooled it
- Diet Quality Indices Used in Australian and New Zealand Adults: A Systematic Review and Critical Appraisal.Nutrients · 2020Pooled it
- Dietary Inflammatory Index and Site-Specific Cancer Risk: A Systematic Review and Dose-Response Meta-Analysis.Advances in nutrition (Bethesda, Md.) · 2018Pooled it
- Pooled it
- Meta-analysis of the association between dietary inflammatory index (DII) and cancer outcomes.International journal of cancer · 2017Pooled it
- Adherence to Mediterranean Diet and Risk of Cancer: An Updated Systematic Review and Meta-Analysis.Nutrients · 2017Pooled it
- Pooled it
- Comparison of mediterranean and healthy eating guideline interventions on the dietary inflammatory index in rheumatoid arthritis: results from a dietary randomised controlled intervention trial.European journal of nutrition · 2026Trial
- How Does Dietary Intake Relate to Dispositional Optimism and Health-Related Quality of Life in GermlineNutrients · 2023Trial
- Nutrition as Modulator of Oxidative Stress in Cancer Prevention and Treatment.International journal of molecular sciences · 2026Review
- The association of depressive symptoms and dietary inflammatory index with frailty in older adults with diabetes.BMC psychiatry · 2026Article
- A cohort study on the association of dietary inflammatory index and a posteriori dietary patterns with lung cancer risk.Scientific reports · 2025Article
- The association between energy-adjusted dietary inflammatory index (E-DII) and lung cancer in 101,755 participants aged 55 years and above: a large prospective cohort.BMC public health · 2025Article
- Dietary Relationships between Obesity and Inflammatory Bowel Diseases: A Narrative Review of Diets Which May Promote Both Diseases.Current gastroenterology reports · 2025Review
- Relationship between dietary inflammatory index and chronic diseases in older U.S. Adults: NHANES 1999-2018.BMC public health · 2025Article
- Nutrition and dietary inflammatory indices of the eight major cuisines of China.BMC nutrition · 2025Article
- Proinflammatory diet is associated with higher pain, disease severity and biochemical parameters associated with inflammation in fibromyalgia.Pain medicine (Malden, Mass.) · 2025Article
- Association of Children's Dietary Inflammatory Index with Depression and Anxiety Symptoms in Adolescents: Mediating Role of Inflammation and Cardiometabolic Risk Factors.Alpha psychiatry · 2025Article
9 more citing papers are in PubMed but not listed here.
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Authors and funding
7 authors at 4 institutions in 4 countries.
Funding
Abstract
purposeTo investigate prospectively the associations of Dietary Inflammatory Index (DII) and Mediterranean Diet Score (MDS) with lung cancer.
methodsWe used data from men and women aged 40-69 years at recruitment in 1990-1994, who were participants in the Melbourne Collaborative Cohort Study (n = 35,303). A total of 403 incident lung cancer cases were identified over an average 18-year follow-up. Hazard ratios (HR) were estimated using Cox regression, adjusting for smoking status and other risk factors, with age as the time metric.
resultsAn inverse correlation was observed between the DII and MDS (ρ = -0.45), consistent with a higher DII being pro-inflammatory and less 'healthy,' while a high MDS reflects a 'healthier' diet. The DII was positively associated with risk of lung cancer in current smokers [HRQ4 vs Q1 = 1.70 (1.02, 2.82); Ptrend = 0.008] (p interaction between DII quartiles and smoking status = 0.03). The MDS was inversely associated with lung cancer risk overall [HR7-9 vs 0-3 = 0.64 (0.45, 0.90); Ptrend = 0.005] and for current smokers (HR7-9 vs 0-3 = 0.38 (0.19, 0.75); Ptrend = 0.005) (p interaction between MDS categories and smoking status = 0.31).
conclusionsThe MDS showed an inverse association with lung cancer risk, especially for current smokers. A high DII, indicating a more pro-inflammatory diet, was associated with risk of lung cancer only for current smokers. A healthy diet may reduce the risk of lung cancer, especially in smokers.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.