Evidence map›Paper›PMID 27294440›Full record

ReviewAnnual review of biochemistry2016

Nucleic Acid-Based Nanodevices in Biological Imaging.

Kasturi Chakraborty, Aneesh T Veetil, Samie R Jaffrey, Yamuna Krishnan

Abstract readReview
In one paragraph

Review in Annual review of biochemistry, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 54 papers.

0numbers the graph read from it
0cells of the map it votes in
54citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

54 citing papers in PubMed.

  1. Review
  2. Quantitative Chemical Imaging of Organelles.Accounts of chemical research · 2024
    Article
  3. Article
  4. Review
  5. Article
  6. A model for collagen secretion by intercompartmental continuities.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  7. Optogenetics meets physiology.Pflugers Archiv : European journal of physiology · 2023
    Article
  8. Article
  9. Recent Advances in DNA Nanomaterials.Nanomaterials (Basel, Switzerland) · 2023
    Review
  10. Article
  11. Nucleic acid nanostructures forApplied physics reviews · 2023
    Review
  12. Review
  13. Review
  14. Review
  15. Article
  16. Article
  17. Article
  18. Engineering Fluorophore Recycling in a Fluorogenic RNA Aptamer.Angewandte Chemie (International ed. in English) · 2021
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Kasturi ChakrabortyDepartment of Chemistry, University of Chicago, Chicago, Illinois 60637; email: kasturi@uchicago.edu , atv@uchicago.edu , yamuna@uchicago.edu.
Aneesh T VeetilDepartment of Chemistry, University of Chicago, Chicago, Illinois 60637; email: kasturi@uchicago.edu , atv@uchicago.edu , yamuna@uchicago.edu.
Samie R JaffreyDepartment of Pharmacology, Weill Medical College of Cornell University, New York, New York 10065; email: srj2003@med.cornell.edu.
Yamuna KrishnanDepartment of Chemistry, University of Chicago, Chicago, Illinois 60637; email: kasturi@uchicago.edu , atv@uchicago.edu , yamuna@uchicago.edu.

Funding

Engineering RNA-activated fluorescence switches for RNA imaging and analyte sensiR01NS064516 · NINDS · WEILL MEDICAL COLL OF CORNELL UNIV · PI JAFFREY, SAMIE R · 2009 to 2018
$3.6M
NINDS NIH HHS R01 NS064516Wellcome Trust
6 · The paper itself

Abstract

The nanoscale engineering of nucleic acids has led to exciting molecular technologies for high-end biological imaging. The predictable base pairing, high programmability, and superior new chemical and biological methods used to access nucleic acids with diverse lengths and in high purity, coupled with computational tools for their design, have allowed the creation of a stunning diversity of nucleic acid-based nanodevices. Given their biological origin, such synthetic devices have a tremendous capacity to interface with the biological world, and this capacity lies at the heart of several nucleic acid-based technologies that are finding applications in biological systems. We discuss these diverse applications and emphasize the advantage, in terms of physicochemical properties, that the nucleic acid scaffold brings to these contexts. As our ability to engineer this versatile scaffold increases, its applications in structural, cellular, and organismal biology are clearly poised to massively expand.

Indexed as

Biosensing TechniquesAptamers, NucleotideBase PairingDNADNA-Directed RNA PolymerasesEscherichia coliIn Situ Hybridization, FluorescenceMicroscopy, Atomic ForceMolecular ImagingNanostructuresNanotechnologyNucleic Acid ConformationRNASpinacia oleraceaAptamers, NucleotideDNADNA-Directed RNA PolymerasesRNAAFMaptamersFISHfunctional bioimaginglive imagingnucleic acid nanodevicesSpinachstructural DNA nanotechnologysuper-resolution microscopy

Identifiers

PMID27294440
PMCPMC5522603

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.