ReviewAnnals of translational medicine2016
Diagnostic algorithms for acute coronary syndrome-is one better than another?
Review in Annals of translational medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 43 citations in OpenAlex.
- Prognostic and functional role of PPAR-alpha and SNP receptor (Leu162Val) in acute coronary syndrome: a potential novel target.Journal, genetic engineering & biotechnology · 2025Article
- Left Ventricular-Arterial Coupling as an Independent Predictor of Adverse Events in Young Patients with ST Elevation Myocardial Infarction-A 3D Echocardiographic Study.Biomedicines · 2024Article
- Diagnostic Role and Methods of Detection of Cardiac Troponins: An Opinion from Historical and Current Points of View.Current cardiology reviews · 2023Review
- Accounting for frailty and multimorbidity when interpreting high-sensitivity troponin I tests in oldest old.Journal of the American Geriatrics Society · 2022Article
- [Current characteristics of methods for determining cardiac troponins and their diagnostic value: a mini-review]Revista de la Facultad de Ciencias Medicas (Cordoba, Argentina) · 2021Review
- Idiosyncratic Drug-Induced Liver Injury (DILI) and Herb-Induced Liver Injury (HILI): Diagnostic Algorithm Based on the Quantitative Roussel Uclaf Causality Assessment Method (RUCAM).Diagnostics (Basel, Switzerland) · 2021Review
- Cardiac Troponins: Contemporary Biological Data and New Methods of Determination.Vascular health and risk management · 2021Review
- Genetic Polymorphism of Angiotensin II Type 1 Receptors and Their Effect on the Clinical Outcome of Captopril Treatment in Arab Iraqi Patients with Acute Coronary Syndrome (Mid Euphrates).Indian journal of clinical biochemistry : IJCB · 2021Article
- Facility Variation in Troponin Ordering Within the Veterans Health Administration.Medical care · 2020Article
- Improved efficiency and cost reduction in the emergency department by replacing contemporary sensitive with high-sensitivity cardiac troponin immunoassay.Acta bio-medica : Atenei Parmensis · 2019Article
- Multicenter observational study on the reliability of the HEART score.Clinical and experimental emergency medicine · 2019Article
- Turkish Society of Cardiology consensus paper on the rational use of cardiac troponins in daily practice.Anatolian journal of cardiology · 2019Article
- Intermittent Typical Angina: Remember Wellens' Syndrome.Advanced journal of emergency medicine · 2019Article
- "Ultra-sensitive" cardiac troponins: Requirements for effective implementation in clinical practice.Biochemia medica · 2018Review
- High-sensitivity cardiac troponin testing in routine practice: economic and organizational advantages.Annals of translational medicine · 2016Review
- Coronary computed tomography angiography (CCTA) and cardiac magnetic resonance (CMR) imaging in the assessment of patients presenting with chest pain suspected for acute coronary syndrome.Annals of translational medicine · 2016Review
- Red blood cell distribution width independently predicts medium-term mortality and major adverse cardiac events after an acute coronary syndrome.Annals of translational medicine · 2016Article
- Predictive significance of detectable cardiac troponin I measured with a contemporary-sensitive assay in a real life experience.Annals of translational medicine · 2016Article
- Evidence and pitfalls in diagnosis and prognostication of acute coronary syndrome.Annals of translational medicine · 2016Article
- Epidemiology of coronary heart disease and acute coronary syndrome.Annals of translational medicine · 2016Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The rather short history of diagnostic algorithms for investigating patients with a suspected acute coronary syndrome (ACS) has led to a constantly evolving and unquestionably chaotic scenario. Although the recent development and introduction of high-sensitivity immunoassays for the measurement of cardiac troponins has represented a paradigm shift for dispersing part of the overwhelming fog, many uncertainties remain, especially concerning the appropriate timing for serial testing and the interpretation of cardiac troponin variations over time. Therefore, the aim of this article is to review the available evidence about diagnostic algorithms for ACS which incorporate the measurement of cardiac troponins, and generate a final algorithm attempting to integrate and harmonize the many clinical and laboratory findings emerged from the recent scientific literature.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.