Evidence map›Paper›PMID 27293842›Full record

ArticleJournal of thoracic disease2016

Long term complications following 54 consecutive lung transplants.

Walther Tabarelli, Hugo Bonatti, Dominique Tabarelli, Miriam Eller, Ludwig Müller, Elfriede Ruttmann, Cornelia Lass-Flörl, Clara Larcher, Christian Geltner

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of thoracic disease, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Article
  6. Heparin-binding protein, lysozyme, and inflammatory cytokines in bronchoalveolar lavage fluid as diagnostic tools for pulmonary infection in lung transplanted patients.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2018
    Article
  7. Article
  8. Successfully physical therapy program for functional respiratory rehabilitation after lung transplant surgery - case report.Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Walther Tabarelli1 Liechtensteinisches Landesspital, Vaduz, Liechtenstein ; 2 Department of Surgery, University of Maryland, Shore Health System, Easton, MD, USA ; 3 State Hospital Natters-Hochzirl, Innsbruck, Austria ; 4 Department of Cardiac Surgery, Innsbruck Medical University, Innsbruck, Austria ; 5 Medical University Innsbruck, Department Hygiene and Microbiology, Innsbruck, Austria ; 6 MB-LAB Mikrobiologisches Labor, Innsbruck, Austria ; 7 Kreisklinik Bad Reichenhall, Pulmonology, Bad Reichenhall, Germany.
Hugo Bonatti1 Liechtensteinisches Landesspital, Vaduz, Liechtenstein ; 2 Department of Surgery, University of Maryland, Shore Health System, Easton, MD, USA ; 3 State Hospital Natters-Hochzirl, Innsbruck, Austria ; 4 Department of Cardiac Surgery, Innsbruck Medical University, Innsbruck, Austria ; 5 Medical University Innsbruck, Department Hygiene and Microbiology, Innsbruck, Austria ; 6 MB-LAB Mikrobiologisches Labor, Innsbruck, Austria ; 7 Kreisklinik Bad Reichenhall, Pulmonology, Bad Reichenhall, Germany.
Dominique Tabarelli1 Liechtensteinisches Landesspital, Vaduz, Liechtenstein ; 2 Department of Surgery, University of Maryland, Shore Health System, Easton, MD, USA ; 3 State Hospital Natters-Hochzirl, Innsbruck, Austria ; 4 Department of Cardiac Surgery, Innsbruck Medical University, Innsbruck, Austria ; 5 Medical University Innsbruck, Department Hygiene and Microbiology, Innsbruck, Austria ; 6 MB-LAB Mikrobiologisches Labor, Innsbruck, Austria ; 7 Kreisklinik Bad Reichenhall, Pulmonology, Bad Reichenhall, Germany.
Miriam Eller1 Liechtensteinisches Landesspital, Vaduz, Liechtenstein ; 2 Department of Surgery, University of Maryland, Shore Health System, Easton, MD, USA ; 3 State Hospital Natters-Hochzirl, Innsbruck, Austria ; 4 Department of Cardiac Surgery, Innsbruck Medical University, Innsbruck, Austria ; 5 Medical University Innsbruck, Department Hygiene and Microbiology, Innsbruck, Austria ; 6 MB-LAB Mikrobiologisches Labor, Innsbruck, Austria ; 7 Kreisklinik Bad Reichenhall, Pulmonology, Bad Reichenhall, Germany.
Ludwig Müller1 Liechtensteinisches Landesspital, Vaduz, Liechtenstein ; 2 Department of Surgery, University of Maryland, Shore Health System, Easton, MD, USA ; 3 State Hospital Natters-Hochzirl, Innsbruck, Austria ; 4 Department of Cardiac Surgery, Innsbruck Medical University, Innsbruck, Austria ; 5 Medical University Innsbruck, Department Hygiene and Microbiology, Innsbruck, Austria ; 6 MB-LAB Mikrobiologisches Labor, Innsbruck, Austria ; 7 Kreisklinik Bad Reichenhall, Pulmonology, Bad Reichenhall, Germany.
Elfriede Ruttmann1 Liechtensteinisches Landesspital, Vaduz, Liechtenstein ; 2 Department of Surgery, University of Maryland, Shore Health System, Easton, MD, USA ; 3 State Hospital Natters-Hochzirl, Innsbruck, Austria ; 4 Department of Cardiac Surgery, Innsbruck Medical University, Innsbruck, Austria ; 5 Medical University Innsbruck, Department Hygiene and Microbiology, Innsbruck, Austria ; 6 MB-LAB Mikrobiologisches Labor, Innsbruck, Austria ; 7 Kreisklinik Bad Reichenhall, Pulmonology, Bad Reichenhall, Germany.
Cornelia Lass-Flörl1 Liechtensteinisches Landesspital, Vaduz, Liechtenstein ; 2 Department of Surgery, University of Maryland, Shore Health System, Easton, MD, USA ; 3 State Hospital Natters-Hochzirl, Innsbruck, Austria ; 4 Department of Cardiac Surgery, Innsbruck Medical University, Innsbruck, Austria ; 5 Medical University Innsbruck, Department Hygiene and Microbiology, Innsbruck, Austria ; 6 MB-LAB Mikrobiologisches Labor, Innsbruck, Austria ; 7 Kreisklinik Bad Reichenhall, Pulmonology, Bad Reichenhall, Germany.
Clara Larcher1 Liechtensteinisches Landesspital, Vaduz, Liechtenstein ; 2 Department of Surgery, University of Maryland, Shore Health System, Easton, MD, USA ; 3 State Hospital Natters-Hochzirl, Innsbruck, Austria ; 4 Department of Cardiac Surgery, Innsbruck Medical University, Innsbruck, Austria ; 5 Medical University Innsbruck, Department Hygiene and Microbiology, Innsbruck, Austria ; 6 MB-LAB Mikrobiologisches Labor, Innsbruck, Austria ; 7 Kreisklinik Bad Reichenhall, Pulmonology, Bad Reichenhall, Germany.
Christian Geltner1 Liechtensteinisches Landesspital, Vaduz, Liechtenstein ; 2 Department of Surgery, University of Maryland, Shore Health System, Easton, MD, USA ; 3 State Hospital Natters-Hochzirl, Innsbruck, Austria ; 4 Department of Cardiac Surgery, Innsbruck Medical University, Innsbruck, Austria ; 5 Medical University Innsbruck, Department Hygiene and Microbiology, Innsbruck, Austria ; 6 MB-LAB Mikrobiologisches Labor, Innsbruck, Austria ; 7 Kreisklinik Bad Reichenhall, Pulmonology, Bad Reichenhall, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDue to the complex therapy and the required high level of immunosuppression, lung recipients are at high risk to develop many different long term complications.

methodsFrom 1993-2000, a total of 54 lung transplantation (LuTx) were performed at our center. Complications, graft and patient survival of this cohort was retrospectively analyzed.

resultsOne/five and ten-year patient survival was 71.4%, 41.2% and 25.4%; at last follow up (4/2010), twelve patients were alive. Of the 39 deceased patients, 26 died from infectious complications. Other causes of death were myocardial infarction (n=1), progressive graft failure (n=1), intracerebral bleeding (n=2), basilary vein thrombosis (n=1), pulmonary emboli (n=1), others (n=7). Surgical complication rate was 27.7% during the first year and 25% for the 12 long term survivors. Perioperative rejection rate was 35%, and 91.6% for the 12 patients currently alive. Infection incidence during first hospitalization was 79.6% (1.3 episodes per transplant) and 100% for long term survivors. Commonly isolated pathogens were cytomegalovirus (56.8%), Aspergillus (29.4%), RSV (13.7%). Other common complications were renal failure (56.8%), osteoporosis (54.9%), hypertension (45%), diabetes mellitus (19.6%).

conclusionsInfection and rejection remain the most common complications following LuTx with many other events to be considered.

Indexed as

complicationscytomegaloviruslong termLung transplantation (LuTx)outcome

Identifiers

PMID27293842
PMCPMC4885970

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.