ReviewEvidence-based complementary and alternative medicine : eCAM2016
Medical Application of Spirulina platensis Derived C-Phycocyanin.
Review in Evidence-based complementary and alternative medicine : eCAM, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 79 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
79 citing papers in PubMed, 200 citations in OpenAlex.
- Antioxidant Efficacy of aMarine drugs · 2022Trial
- Evaluating the Efficacy and Safety ofAntioxidants (Basel, Switzerland) · 2026Article
- Review
- Spirulina and Its Bioactive Compounds as Multi-Target Anticancer Agents: Mechanisms, Immune Modulation, and Translational Potential.Medical sciences (Basel, Switzerland) · 2026Review
- In Silico and In Vitro Therapeutic Effects of Phycocyanin Against Lipid Micelle and/or Endotoxin-Induced Oxidative Damage and Barrier Dysfunction in Human Intestinal Epithelial Cells Model.Molecular nutrition & food research · 2026Article
- Microalgae as a Source of Photosensitizers: Analytical Strategies and Biomedical Use in Photodynamic Therapy.Pharmaceuticals (Basel, Switzerland) · 2026Review
- Cyanobacterial Biofactories Beyond Model Strains: Exploratory Screening of Immunomodulatory Activity inPlants (Basel, Switzerland) · 2025Article
- Article
- Study of the Physicochemical and Phytochemical Parameters Together with Antibacterial Properties of Conventionally and Organically Cultivated Spirulina (Life (Basel, Switzerland) · 2025Article
- In vitro and in silico analysis of the anti-proliferative effects of Spirulina platensis on A549 lung cancer cells.Scientific reports · 2025Article
- Production and Applications of Cyanobacterial Phycocyanin: Trends and Prospects.Indian journal of microbiology · 2025Article
- Response surface methodology-based approach for enhanced C-Phycocyanin production from3 Biotech · 2025Article
- Article
- Application of aqueous biphasic systems based on pluronic copolymer and deep eutectic solvent to achieve purified C phycocyanin.Scientific reports · 2025Article
- Effects of Phytogenic Feed Additive on Production Performance, Slaughtering Performance, Meat Quality, and Intestinal Flora of White-Feathered Broilers.Veterinary sciences · 2025Article
- Phycochemistry and pharmacological significance of filamentous cyanobacterium Spirulina sp.Bioresources and bioprocessing · 2025Review
- Comparison of Pressurized Water Extraction With Ultrasound Assisted Extraction for Isolation of Phycobiliproteins From Arthrospira platensis (Spirulina).Phytochemical analysis : PCA · 2025Article
- In-house chromogenic anti-factor Xa assay: development, validation, and identification of factors predicting APTT discordance.Frontiers in medicine · 2025Article
- Article
- Spectral Characteristics, In Silico Perspectives, Density Functional Theory (DFT), and Therapeutic Potential of Green-Extracted Phycocyanin fromInternational journal of molecular sciences · 2024Article
19 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Along with the development of marine biological pharmaceutical research, high-effective and low-toxic drugs and functional foods isolated from marine organisms have become a new field of pharmacy and bromatology. The pharmacological actions, such as anti-inflammation, antioxidation, antitumor, immunological enhancement, and hepatorenal protection of C-phycocyanin (C-PC) from Spirulina platensis, have been reported, and C-PC has important value of development and utilization either as drug or as functional food. There are many researches about the various pharmacological actions and mechanisms of C-PC, but related reports are only to some extent integrated deeply and accurately enough, which put some limitations to the further application of C-PC in medicine. Particularly, with the improvement of living standards and attention to health issues, C-PC being a functional food is preferred by more and more people. C-PC is easy to get, safe, and nontoxic; thus, it has a great potential of research and development as a drug or functional food. Here, the separation and purification, physicochemical properties, physiological and pharmacological activities, safety, and some applications are reviewed to provide relevant basis for the development of natural medicine and applied products.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.