ArticleCase reports in oncology
Pseudocirrhosis in Gastric Cancer with Diffuse Liver Metastases after a Dramatic Response to Chemotherapy.
Article in Case reports in oncology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.
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Who cites it
7 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.
- Pseudocirrhosis and portal hypertension in patients with metastatic cancers: a systematic review and meta-analysis.Scientific reports · 2022Pooled it
- Isolated serosal liver infiltration mimicking cirrhosis in gastroesophageal junction adenocarcinoma: A report of 2 cases.Radiology case reports · 2026Article
- Pseudocirrhosis: A Case Series with Clinical and Radiographic Correlation and Review of the Literature.Digestive diseases and sciences · 2024Review
- Clinical Outcomes of Metastatic Breast Cancer in Patients Having Imaging Liver Pseudocirrhosis with or without Evident Varices.The oncologist · 2022Article
- Pseudocirrhosis after chemotherapy for gastric cancer with diffuse liver metastases: A case report.Molecular and clinical oncology · 2022Article
- Pseudocirrhosis caused by lung adenocarcinoma with diffuse liver metastasis: An autopsy case report.Thoracic cancer · 2021Article
- A fatal case of metastatic gastric adenocarcinoma mimicking cirrhosis.Autopsy & case reports · 2021Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We present the first reported case of pseudocirrhosis arising after a dramatic response to chemotherapy in metastatic gastric cancer. A 74-year-old man was diagnosed with gastric adenocarcinoma having multiple liver metastases. His general condition was poor, with an Eastern Cooperative Oncology Group performance status of 3, inadequate oral intake, and jaundice (total bilirubin 2.8 mg/dl). Chemotherapy with oxaliplatin, l-leucovorin, and 5-fluorouracil (modified FOLFOX-6) was initiated. After four treatment cycles, he experienced a marked regression of liver metastases; however, he developed massive ascites with a lobular liver surface and segmental atrophy, which were consistent with pseudocirrhosis. Chemotherapy was continued along with ascites management. Thereafter, ascites disappeared, and a complete response of the metastatic lesions was achieved at 11 months after initial treatment. He had no evidence of disease progression at 30 months after initial chemotherapy. This report suggests clinicians should recognize this entity, even in gastric cancer metastatic to the liver.
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