ArticleTheoretical computer science2016
A strand graph semantics for DNA-based computation.
Article in Theoretical computer science, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed.
- A Generalizable Screening Platform for Developing Functional Aptasensors.Analytical chemistry · 2025Article
- A geometric framework for reaction enumeration in computational nucleic acid devices.Journal of the Royal Society, Interface · 2023Article
- Design and Simulation of an Autonomous Molecular Mechanism Using Spatially Localized DNA Computation.Interdisciplinary sciences, computational life sciences · 2023Article
- A domain-level DNA strand displacement reaction enumerator allowing arbitrary non-pseudoknotted secondary structures.Journal of the Royal Society, Interface · 2020Article
- DNA-strand molecular beacon optical processor.Heliyon · 2019Article
- Automated sequence-level analysis of kinetics and thermodynamics for domain-level DNA strand-displacement systems.Journal of the Royal Society, Interface · 2018Article
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
DNA nanotechnology is a promising approach for engineering computation at the nanoscale, with potential applications in biofabrication and intelligent nanomedicine. DNA strand displacement is a general strategy for implementing a broad range of nanoscale computations, including any computation that can be expressed as a chemical reaction network. Modelling and analysis of DNA strand displacement systems is an important part of the design process, prior to experimental realisation. As experimental techniques improve, it is important for modelling languages to keep pace with the complexity of structures that can be realised experimentally. In this paper we present a process calculus for modelling DNA strand displacement computations involving rich secondary structures, including DNA branches and loops. We prove that our calculus is also sufficiently expressive to model previous work on non-branching structures, and propose a mapping from our calculus to a canonical
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