Evidence map›Paper›PMID 27293113›Full record

ReviewJournal of neurogenetics2016

Motivated state control in larval zebrafish: behavioral paradigms and anatomical substrates.

Eric J Horstick, Thomas Mueller, Harold A Burgess

Abstract readReview
In one paragraph

Review in Journal of neurogenetics, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. A comparative analysis ofFrontiers in behavioral neuroscience · 2022
    Article
  8. Review
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Eric J Horsticka Division of Developmental Biology , Eunice Kennedy Shriver National Institute of Child Health and Human Development , Bethesda , MD , USA ;
Thomas Muellerb Division of Biology , Kansas State University , Manhattan , KS , USA.
Harold A Burgessa Division of Developmental Biology , Eunice Kennedy Shriver National Institute of Child Health and Human Development , Bethesda , MD , USA ;

Funding

Mentoring CoreP20GM103418 · NIGMS · UNIVERSITY OF KANSAS MEDICAL CENTER · PI Douglas E Wright · 2012 to 2026
$63.0M
Neuronal Circuits Controlling Behavior: Genetic Analysis in ZebrafishZIAHD008884 · NICHD · EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH & HUMAN DEVELOPMENT · PI BURGESS, HAROLD · 2009 to 2025
$21.3M
Intramural NIH HHS Z99 HD999999NIGMS NIH HHS P20 GM103418
6 · The paper itself

Abstract

Over the course of each day, animals prioritize different objectives. Immediate goals may reflect fluctuating internal homeostatic demands, prompting individuals to seek out energy supplies or warmth. At other times, the environment may present temporary challenges or opportunities. Homeostatic demands and environmental signals often elicit persistent changes in an animal's behavior to meet needs and challenges over extended periods of time. These changes reflect the underlying motivational state of the animal. The larval zebrafish has been established as an effective genetically tractable vertebrate system to study neural circuits for sensory-motor reflexes. Fewer studies have exploited zebrafish to study brain circuits that control motivated behavior. In part this is because appropriate conceptual frameworks, anatomical knowledge, and behavioral paradigms are not yet well established. This review sketches a general conceptual framework for studying motivated state control in animal models, how this applies to larval zebrafish, and the current knowledge on neuroanatomical substrates for state control in this model.

Indexed as

AnimalsBehavior, AnimalBrainLarvaMotivationNeural PathwaysZebrafishBehaviormotivationneuromodulatorzebrafish

Identifiers

PMID27293113
PMCPMC6223122

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.