ArticleScientific reports2016
Investigation of the cellular reprogramming phenomenon referred to as stimulus-triggered acquisition of pluripotency (STAP).
Article in Scientific reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
4 citing papers in PubMed.
- Postnatal Pluripotent Cells: Quarter of a Century of Research.Bulletin of experimental biology and medicine · 2021Article
- Cytoplasmic dsRNA induces the expression ofThe Journal of biological chemistry · 2019Article
- Pluripotent Stem Cells in Adult Tissues: Struggling To Be Acknowledged Over Two Decades.Stem cell reviews and reports · 2017Review
- Results of an attempt to reproduce the STAP phenomenon.F1000Research · 2016Article
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Authors and funding
1 author.
Funding
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Abstract
In January 2014, it was reported that strong external stimuli, such as a transient low-pH stressor, was capable of inducing the reprogramming of mammalian somatic cells, resulting in the generation of pluripotent cells. This cellular reprograming event was designated 'stimulus-triggered acquisition of pluripotency' (STAP) by the authors of these reports. However, after multiple instances of scientific misconduct in the handling and presentation of the data were brought to light, both reports were retracted. To investigate the actual scientific significance of the purported STAP phenomenon, we sought to repeat the original experiments based on the methods presented in the retracted manuscripts and other relevant information. As a result, we have concluded that the STAP phenomenon as described in the original studies is not reproducible.
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Registered trials
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