ArticleJournal of neuro-oncology2016
Stereotactic biopsy of brainstem lesions: 21 years experiences of a single center.
Article in Journal of neuro-oncology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 3 of them syntheses that pooled it.
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Who cites it
22 citing papers in PubMed, 3 syntheses or guidelines pooled it, 45 citations in OpenAlex.
- Diagnostic yield, safety, and molecular-era clinical utility of stereotactic biopsy for brainstem lesions: a contemporary systematic review and meta-analysis.Frontiers in surgery · 2026Pooled it
- Complications after frame-based stereotactic brain biopsy: a systematic review.Neurosurgical review · 2021Pooled it
- Stereotactic Biopsy for Brainstem Lesions: A Meta-analysis with Noncomparative Binary Data.Cancer control : journal of the Moffitt Cancer CenterPooled it
- Clinician perspectives on the clinical utility of Belay Summit™ 2.0 cerebrospinal fluid test - A mixed methods study.The journal of liquid biopsy · 2026Article
- Intraoperative tract mapping through the biopsy cannula during stereotactic biopsy of brainstem lesions: a prospective feasibility study.Journal of neuro-oncology · 2026Article
- Fluorescence-aided stereotactic needle biopsies for brain tumors: experience on 516 cases.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2026Article
- Voxel-based evaluation of hemorrhage risk in brain biopsies.Neurosurgical review · 2026Article
- Efficacy and safety of frameless versus frame-based stereotactic biopsy for brainstem lesions: A comparison demonstrating comparable outcomes with frameless technique.Surgical neurology international · 2026Article
- Evaluating hemorrhagic risks using intratumoral susceptibility signals in stereotactic brain biopsies.Neurosurgical review · 2025Article
- Anticipating complications in stereotactic brain biopsy: a predictive approach.Neurosurgical review · 2025Article
- Frame-based stereotactic biopsies of brainstem lesions - Monocentric comparison of the transfrontal and the suboccipital-transcerebellar approach over a 16-year period.Neurosurgical review · 2024Article
- Stereotactic frame-based biopsy of infratentorial lesions via the suboccipital-transcerebellar approach with the Zamorano-Duchovny stereotactic system-a retrospective analysis of 79 consecutive cases.Acta neurochirurgica · 2024Article
- The risk factors of hemorrhage in stereotactic needle biopsy for brain lesions in a large cohort: 10 years of experience in a single center.Chinese neurosurgical journal · 2022Article
- Roles and outcomes of stereotactic biopsy for adult patients with brainstem lesion.Journal of neuro-oncology · 2022Article
- A Case Series of Stereotactic Biopsy of Brainstem Lesions through the Transfrontal Approach.Journal of neurological surgery reports · 2022Article
- The Role of Stereotactic Frame-Based Biopsy for Brainstem Tumors in the Era of Molecular-Based Diagnosis and Treatment Decisions.Current oncology (Toronto, Ont.) · 2022Article
- Frameless robot-assisted stereotactic biopsies for lesions of the brainstem-a series of 103 consecutive biopsies.Journal of neuro-oncology · 2022Article
- Management and outcome of pediatric brainstem and cerebellar peduncular low-grade gliomas: a retrospective analysis of 62 cases.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2022Article
- Outpatient stereotactic brain biopsies.Neurosurgical review · 2022Article
- Indicators of correct targeting in stereotactic biopsy of intracranial lesions.Surgical neurology international · 2022Article
Corrections and comments
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Authors and funding
8 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Stereotactic biopsies are procedures performed to obtain tumor tissue for diagnostic examinations. Cerebral lesions of unknown entities can safely be accessed and tissue can be examined, resulting in correct diagnosis and according treatment. Stereotactic procedures of lesions in highly eloquent regions such as the brainstem have been performed for more than two decades in our department. In this retrospective study we focus on results, approaches, modalities of anesthesia, and complications. We performed a retrospective analysis of our prospective database, including 26 patients who underwent stereotactic biopsy of the brainstem between April 1994 and June 2015. All of the patients underwent preoperative MRI. Riechert-Mundinger-frame was used before 2000, thereafter the Leksell stereotactic frame was used. After 2000 entry and target points were calculated by using BrainLab stereotactic system. We evaluated histopathological results as well as further treatment; additionally we compared complications of local versus general anesthesia and complications of a frontal versus a trans-cerebellar approach. Median age of all patients was 33 years, and median number of tissue samples taken was 12. In all patients a final histopathological diagnosis could be established. 5 patients underwent the procedure under local anesthesia, 21 patients in general anesthesia. In 19 patients a frontal approach was performed, while in 7 patients a trans-cerebellar approach was used. Complications occurred in five patients. Thereby no significant difference was found with regard to approach (frontal versus trans-cerebellar) or anesthesia (local versus general). Stereotactic biopsies even of lesions in the brainstem are a save way to obtain tumor tissue for final diagnosis, resulting in adequate treatment. Approach can be trans-cerebellar or frontal and procedure can be performed either under local or general anesthesia without significant differences concerning complication rate.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.